PURPOSE In Thailand, there has been no study determining the concomitant use of medications, known to potentially interact with warfarin, in patients receiving warfarin therapy. This paper examined the frequency of which specific interacting drugs were concomitantly used in warfarin users. METHODS We retrospectively examined the database of warfarin outpatient medical records from a regional ...

OBJECTIVE To explore healthcare professionals' views about the benefits and challenges of using information technology (IT) resources for educating patients about their warfarin therapy. METHODS A cross-sectional survey of both community and hospital-based healthcare professionals (e.g., doctors, pharmacists and nurses) involved using a purpose-designed questionnaire. The questionnaires were ...

scribe WISN in a 52-year-old man with protein C and S deficiency four years after warfarin initiation (5). Tillou et al. describe an 84-year-old male with WISN after six months of therapy for PE with DVT (6). Gaikwad et al. describe a 31-year-old male with a DVT who presented with WISN after two months of warfarin (7). Scarff et al. describe a 43-year-old female with recent aortic and mitral va...

Warfarin-related nephropathy (WRN) is a recently recognized condition in patients with chronic kidney disease (CKD). WRN is clinically detected as an episode of unexplained acute kidney injury (AKI). It is defined as a serum creatinine (sCR) increase >0.3 mg/dL (26.5 μmol/L) within one week of an international normalized ratio (INR) measurement >3.0 in a patient treated with warfarin without cl...

IMPORTANCE The risk of bleeding and recurrent venous thromboembolism (VTE) among patients receiving long-term warfarin sodium therapy for secondary VTE prevention who require temporary interruption of anticoagulant therapy for surgery or invasive diagnostic procedures has not been adequately described. OBJECTIVE To describe the rates of clinically relevant bleeding and recurrent VTE among pat...

BACKGROUND AND PURPOSE Antithrombotic therapy can prevent strokes and transient ischemic attacks (TIAs) in carefully selected patients who have chronic nonvalvular atrial fibrillation (NVAF). Our objectives were 3-fold: to document the use of warfarin and aspirin therapy in Missouri Medicare beneficiaries with chronic NVAF; to identify factors associated with warfarin and aspirin underuse; and ...

BACKGROUND Warfarin related nephropathy is one of the potential complications of warfarin therapy. Despite the well described histological entity, the clinical course and approach to warfarin related nephropathy in patients requiring life-long anticoagulation is however not well described in the literature. CASE PRESENTATION We report the clinical course of a 56 years old Chinese lady who pre...

Background: Warfarin has been the mainstay oral anticoagulant agent for the last several decades despite its narrow therapeutic index. It is critical for health professionals to have better knowledge and understanding on oral anticoagulant management and on how to give counseling for patients on this therapy. This study assessed healthcare professionals’ knowledge and counseling practice on war...

neonatal purpura fulminans is a rare and life threatening disease that can be inherited or acquired in etiology. it manifests as dic and extensive subcutaneous thrombosis. the condition is often fatal unless there is prompt diagnosis, and judicious therapy. the most important causes of this condition are infections and congenital deficiency of anticoagulant proteins c and s.in the case of pc (p...

BACKGROUND Warfarin therapy is effective for the prevention of stroke in patients with atrial fibrillation. However, warfarin therapy is underutilized even among ideal anticoagulation candidates. The purpose of this study was to examine the use of warfarin in both inpatients and outpatients with atrial fibrillation within a Veterans Affairs (VA) hospital system. METHODS This retrospective med...