Discriminative classifiers are a popular approach to solving classification problems. However one of the problems with these approaches, in particular kernel based classifiers such as Support Vector Machines (SVMs), is that they are hard to adapt to mismatches between the training and test data. This paper describes a scheme for overcoming this problem for speech recognition in noise by adaptin...

In this paper we introduce a new analytical approach to environment compensation for speech recognition. Previous attempts at solving analytically the problem of noisy speech recognition have either used an overly-simplified mathematical description of the effects of noise on the statistics of speech or they have relied on the availability of large environment-specific adaptation sets. Some of ...

Computational methods involving virtual screening could potentially be employed to discover new biomolecular targets for an individual molecule of interest (MOI). However, existing scoring functions may not accurately differentiate proteins to which the MOI binds from a larger set of macromolecules in a protein structural database. An MOI will most likely have varying degrees of predicted bindi...

BACKGROUND Catheter ablation can reduce episodes of ventricular tachycardia (VT) after myocardial infarction (MI). However, the optimal endpoint of the ablation procedure remains unclear. METHODS Fifty-one consecutive patients who received catheter ablation for VT after MI were included. The procedures targeted the isthmus of all the induced, sustained VTs. When the patients with induced VTs ...

BACKGROUND Catheter ablation of ventricular tachycardia (VT) is limited by difficulty in identifying suitable sites for ablation. This study assesses use of a system capable of simultaneous endocardial mapping of the human left ventricle to map and guide radiofrequency (RF) catheter ablation of VT. METHODS AND RESULTS A catheter-mounted noncontact multielectrode array was used to reconstruct ...

BACKGROUND Idiopathic left bundle-branch block (LBBB)-like ventricular tachycardia (VT) is considered to originate in the right ventricular outflow tract (RVOT) or from the aortic root. Both regions are derived from the embryonic outflow tract. We now report that also the pulmonary trunk can give rise to VT, suggesting a common etiology of these tachycardias. METHODS AND RESULTS We studied 6 ...

The debate on the benefits of trust or distrust in groups has generated a substantial amount of research that points to the positive aspects of trust in groups, and generally characterizes distrust as a negative group phenomenon. Therefore, many researchers and practitioners assume that trust is inherently good and distrust is inherently bad. However, recent counterintuitive evidence obtained f...

Research on virtual teams (VTs) has proliferated in the last decades. However, few clear and consistent theoretical attempts to integrate the literature on VTs in a systemic way have emerged. This paper uses the complex adaptive systems (CAS) perspective to integrate the literature on emergent states in VTs. According to this general framework, VT effectiveness depends on the interaction betwee...