Zusammenfassung Es wurden zwei empirische Studien durchgeführt. In der einen Studie konnten Internetnutzer ihr Suchverhalten aus ihrer Sicht in einer Online Umfrage beschreiben. Die Fragen orientieren sich an den Ergebnissen früherer Studien und sind durch neue Fragestellungen bei der Online Suche erweitert worden. In der anderen Studie wurden vier weltweit Datensätze von Suchanfragen generiert...

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Die Aussagekraft betrieblicher Daten kann durch die Nutzung von Unternehmensvergleichen wesentlich erhöht werden. An einem Beispiel von Gesundheitsdaten beim Milchrind werden die informationstechnologischen Voraussetzungen zur Umsetzung eines entsprechenden Konzeptes erläutert. Schwerpunkte bilden dabei die Bereitstellung, die Vergleichbarkeit, die Übertragung und die Präsentation der Daten.

Seven new cases of pregnancy combined with von Willebrand's disease have been reported. Altogether the patients had 11 deliveries, and one abortion after 10 weeks' gestation. The diagnosis was based on the determination of the bleeding time, factor VIII coagulant activity (VIII C), factor VIII-related antigen (VIII RAg) and the ristocetin cofactor (VIII RCoF). Two of our 6 parturients showed pr...

Von Willebrand disease (vWD) is the most common inherited bleeding disorder. It is due to deficiency of von Willebrand factor (vWF) which may be either quantitative or qualitative. There are 3 types of vWD out of which Type III is the rarest but the most severe. We report a 27 years second gravida diagnosed with vWD in her index pregnancy. Though her antenatal period was uneventful, she develop...

The wide clinical spectrum of von Willebrand disease (VWD), its complex pathophysiology and its classification into distinct quantitative (type 1 or type 3) and qualitative (type 2) types with further subtle distinctions have prevented most clinicians from establishing a straightforward approach to diagnosing and treating this inherited bleeding disorder. The results of studies involving large ...

Von Willebrand disease (VWD), the most common genetic bleeding disorder, is characterised by a quantitative or qualitative defect of von Willebrand factor (VWF). Patients with VWD suffer from mucocutaneous bleeding, of severity usually proportional to the degree of VWF defect. In particular, gastrointestinal bleeding associated with angiodysplasia is often a severe symptom of difficult manageme...

To characterize the heterogeneity of severe (type III) von Willebrand disease (vWD), plasma and platelet von Willebrand factor antigen (vWF:Ag) and ristocetin cofactor activity (Ricof) were measured in 28 obligatory heterozygotes (ie, parents or children of probands from 15 different kindreds with severe vWD). On the average, heterozygotes had low levels of vWF in both platelets and plasma. The...