نتایج جستجو برای: vntr genotyping
تعداد نتایج: 25021 فیلتر نتایج به سال:
Nicotine addiction, related to cigarette smoking, develops as a product of the complex interactions between social, environmental and genetic factors. Genes encoding the components of the dopaminergic system are thought to be associated with smoking. Literature data showed not only an association, but also a lack of association between variable number of tandem repeats (VNTR) polymorphism locat...
online | memorias.ioc.fiocruz.br Bovine tuberculosis (BTB) is an infectious disease primarily caused by Mycobacterium bovis, which affects a wide range of mammals, including humans (Amanfu 2006). M. bovis is a member of the Mycobacterium tuberculosis complex (MTBC), which also includes M. tuberculosis, Mycobacterium africanum, Mycobacterium canetti, Mycobacterium microti, Mycobacterium caprae a...
BACKGROUND Human leukocyte antigens (HLA) complex and INS-IGF2 5'VNTR loci are principal determinants of the risk of type 1 diabetes mellitus (T1DM). Carriage of class III allele is protective, while class I/I homozygosity increases the risk of T1DM. MATERIAL AND METHODS HLA and 5'VNTR allele frequencies were summarised and multivariate logistic regression models with interaction evaluation w...
OBJECTIVE The objective of this study was to examine the associations between insulin gene variable number of tandem repeats (INS VNTR) and insulin-like growth factor 1 (IGF1) gene promoter region polymorphisms with body composition in early childhood. METHODS This study was embedded in an ongoing prospective cohort study. Growth in early childhood (body mass index, total subcutaneous fat mas...
Mycobacterium bovis is the causative agent of bovine tuberculosis (TB), a disease that affects approximately 5% of Argentinean cattle. Among the molecular methods for genotyping, the most convenient are spoligotyping and variable number of tandem repeats (VNTR). A total of 378 samples from bovines with visible lesions consistent with TB were collected at slaughterhouses in three provinces, yiel...
Genotypic analysis of Mycobacterium tuberculosis in Bangladesh and prevalence of the Beijing strain.
Genotypic analysis was performed on 48 Mycobacterium tuberculosis complex strains collected from a hospital in Dhaka city. Deletion analysis showed that the isolates were all M. tuberculosis; 13 of them were found to be of the "ancestral" type, while 35 were of the "modern" type, indicating that both endemic (ancestral type) and epidemic (modern type) strains cause tuberculosis in Bangladesh. G...
Variation at the insulin gene (INS-)VNTR (variable number of tandem repeats) minisatellite polymorphism has been reported to be associated with both early growth and adult metabolic phenotypes. However, the samples studied have been small and the relationship between INS-VNTR variation and parameters of early growth inconsistent, with four previous studies producing conflicting results. We have...
Although historically considered as junk-DNA, tandemly repeated sequence motifs can affect human phenotype. For example, variable number tandem repeats (VNTR) with embedded enhancers have been shown to regulate gene transcription. The post-zygotic variation is the presence of genetically distinct populations of cells in an individual derived from a single zygote, and this is an understudied asp...
A great deal of data support the direct involvement of the vascular endothelium, complex cellular interactions, and global inflammation-mediated cell activation in triggering vasoocclusive crisis (VOC) in sickle cell disease (SCD) [1]. In the transgenic mice model for SCD, it has been shown that nitric oxide (NO) protects the mice from VOC [2]. Elevated plasma levels of certain proinflammatory ...
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