The aims of the present study are to examine in-vitro antifungal activity crude extracts Sudanese medicinal plants against two fungal species in order verify their possible inhibitory and identify bioactive compounds responsible for observed activity. Minimum concentration (MIC) phytochemical screening were investigated most active detect group secondary metabolites. Agar diffusion method was u...

one of the most significant issues in pharmaceutical industries, prior to commercializationof a pharmaceutical preparation is the “preformulation” stage. however, far too attention hasbeen paid to verification of the software assisted statistical designs in preformulation studies.the main aim of this study was to report a step by step preformulation approach for a semisolidpreparation based on ...

background and objectives: current chemotherapies of cutaneous leihmaniasis have faced to some problems and limitations; development of new leishmanicidal drugs from different sources like herbal plants, are crucially important. the objective of the present study was evaluation of in vitro activity of alkanna frigida extracts in comparison with glucantime against leishmania major . materials an...

abstract background autologus platelet gel is easy to prepare and is relatively low cost. the aim of this study was to prepare and evaluate in vitro efficacy of autologus platelet gel. materials and methods in this experimental study, platelet concentrate and platelet poor plasma were prepared with aphaeresis method. thrombin was prepared by mixing the plasma with calcium. thrombin activity lev...

Synthetic cannabinoids (SCs) are an emerging class of abused drugs that differ from each other and the phytocannabinoid ∆9-tetrahydrocannabinol (THC) in their safety and cannabinoid-1 receptor (CB1R) pharmacology. As efficacy represents a critical parameter to understanding drug action, the present study investigated this metric by assessing in vivo and in vitro actions of THC, two well-charact...

The control of ticks with vaccines is of global interest. Experimental vaccines incorporate new technologies as soon as they are available. Historically, the main vaccine studies have focused on the one-host cattle tick Rhipicephalus microplus, and efficacy evaluations have been standardised for this tick species. On the other hand, evaluations of vaccine candidates for three-host ticks are bei...