We describe a new triborheometry fixture that can be utilized with a commercial torsional rheometer in order to explore the coupled rheological and tribological properties of complex fluids and solid-liquid systems. The fixture is self-leveling and both the normal load and the sample gap can be monitored or controlled. At large gaps, the fixture imposes an approximately constant shear rate on t...

The viscometric functions for shear flow as predicted by the inextensible reptating rope model have been analysed numerically and analytically. The results obtained are compared with the predictions of the Curtiss-Bird theory. It is shown that if the correlation length of the rope is small as compared to its contour length significant deviations from the Curtiss-Bird theory are obtained. Result...

The interaction of native calf thymus DNA (ctDNA) with solifenacin succinate (SFS) was investigated under simulated physiological conditions by multi-spectroscopic techniques and viscometric measurements. It concluded that SFS could intercalate into the base pairs of ctDNA, and the fluorescence quenching by ctDNA was static quenching type. Thermodynamic parameters calculated suggested that the ...

The following compounds, which possess anti-R-plasmid activity (Hahn and Ciak, 1976) in decreasing order, were shown by viscometric titration to change systematically the superhelical density of closed circular PM2 deoxyribonucleic acid in the manner of intercalators: ethidium bromide, quinacrine, acridine orange, quinine, chlorpromazine, chloroquine, and methylene blue. The same effect was cau...

A new viscometric technique, capable of detecting DNA strand breaks and alkali-labile sites by monitoring time-dependent changes of DNAreduced viscosity, has been used to analyze dose-response curves for the induction of DNA damage in liver of rats treated with single p.o. doses of sixteen A-nit roso compounds. Statistically significant changes of DNA viscometric parameters, which are considere...