Vegetative propagation of potato allows the dissemination of viruses that can cause drastic drops in tuber yield. Potato virus Y (PVY) is one of the most important viruses of potato due to the non-persistent mode of transmission through vector insects. Genetic resistance is the recommended control measure since the chemical control of vector insects is not effective. This study aimed to identif...

The current method for creation of vaccinia virus (VACV) vectors involves using a selection and purification marker, however inclusion of a gene without therapeutic value in the resulting vector is not desirable for clinical use. The Cre-LoxP system has been used to make marker-free Poxviruses, but the efficiency was very low. To obtain a marker-free VACV vector, we developed marker gene excisi...

objective: our research attempted to show that mouse dental pulp stem cells (dpscs) with characters such as accessibility, propagation and higher proliferation rate can provide an improved approach for generate bone tissues. with the aim of finding and comparing the differentiation ability of mesenchymal stem cells derived from dpscs into osteoblast and osteoclast cells; morphological, molecula...

Immune suppression during measles accounts for most of the morbidity and mortality associated with the virus infection. Experimental study of this phenomenon has been hampered by the lack of a suitable animal model. We have used the cotton rat to demonstrate that mitogen-induced proliferation of spleen cells from measles virus-infected animals is impaired. Proliferation inhibition is seen in al...

Serum soluble urokinase-type plasminogen activator receptor (suPAR) is a glycoprotein secreted during infections and inflammation . Urokinase-type plasminogen activator (uPA) is secreted by polymorphonuclear neutrophils (PMN) and macrophages; then uPA binds to membrane urokinase-type plasminogen activator receptor (uPAR) . suPAR is formed by cleaved from the uPAR . suPAR is expressed in various...

various cell proliferation markers are used as diagnostic and prognostic tools in oral lesions. simultaneous evaluation of these markers can increase the precision of estimation of the proliferative status of different tissues. in this study we investigated the expression of pcna and ki-67 as markers of cell proliferation in 15 paraffin embedded samples of each dental follicle, dentigerous cyst...

Objective(s): Production of a recombinant and immunogenic antigen using dengue virus type-3 envelope protein is a key point in dengue vaccine development and diagnostic researches. The goals of this study were providing a recombinant protein from dengue virus type-3 envelope protein and evaluation of its immunogenicity in mice. Materials and Methods: Multiple amino acid sequences of different i...