Viral Gastroenteritis Unit, Division of Viral Diseases, Center for Infectious Diseases, Centers for Disease Control, Atlanta, Georgia 303331*; Laboratory of Virus Morphology, Institute of Virology, Chinese Academy of Preventive Medicine, Beijing, China2; Department of Virology and Epidemiology, Baylor College of Medicine, Houston, Texas 7703O3; Department of Pediatrics, The Johns Hopkins Hospit...

Although maps of intracellular interactions are increasingly well characterized, little is known about large-scale maps of host-pathogen protein interactions. The investigation of host-pathogen interactions can reveal features of pathogenesis and provide a foundation for the development of drugs and disease prevention strategies. A compilation of experimentally verified interactions between HIV...

High-risk human papillomaviruses (HPVs) infect epithelial cells and induce viral genome amplification upon differentiation. HPV proteins activate DNA damage repair pathways by inducing high numbers of breaks in both cellular DNAs.

The generation of computational models is an alternative route to obtain reliable structures for the oligomeric state of membrane proteins. A strategy has been developed to search the conformational space of all possible assemblies in a reasonable time, taking symmetry considerations into account. The methodology tested on M2 from influenza A, shows an excellent agreement with established struc...

Ovis aries papillomavirus 3 (OaPV3) is an epidermotropic PV reported in sheep cutaneous squamous cell carcinoma (SCC). The presence of OaPV3 DNA and its transcriptional activity SCC, as well vitro transforming properties, suggest a viral etiology for this neoplasm. Nevertheless, the reactome associated with viral-host interaction still unexplored. Here, we investigated compared proteomic profil...

Mass spectrometry (MS) is one of the key technologies used in proteomics. The majority studies carried out using proteomics have focused on identifying proteins biological samples such as human plasma to pin down prognostic or diagnostic biomarkers associated with particular conditions diseases. This study aims quantify microbial (viral and bacterial) healthy plasma. MS data were searched again...

Corona virus disease 2019 (COVID-19) endemic has havoc on the world; causative of pandemic is SARS CoV-2. Pharmaceutical companies and academic institutes are in continuous efforts to identify anti-viral therapy or vaccines, but most significant challenge faced highly evolving genome CoV-2, which imparting evolutionary selective benefits virus. To understand viral mutations, we have retrieved n...

Coronavirus Disease 2019 (COVID-19) is a viral pneumonia emerged in December 2019 in Wuhan, China. Its cause is a new virus from the coronavirus family scientifically named Coronavirus Acute Respiratory Syndrome 2 (SARS-CoV-2). In this review study, articles published in English until March 23, 2020 on new coronavirus infection were reviewed. These articles are obtained by searching in PubMed, ...