Bone cement augmentation of pedicle screw is an important surgical procedure for osteoporotic vertebral collapse, preventing screw loosening, migration or back-out. Bone cement leakage may develop and mostly does not compress the peripheral tissue of the vertebral body including the spinal cord. However, to our best knowledge, bone cement leakage into the inferior vena cava during cement augmen...

We investigated histological and compressive properties of a calcium phosphate bone cement (BoneSource (CPC); Stryker Orthopaedics, Mahwah, New Jersey) plus carboxymethyl cellulose (CMC) using a sheep vertebral bone void model. Bone voids were surgically created in L3 and L5 in each of 40 sheep, and the voids were filled with the cement. Histological and radiographic evaluations were performed ...

We performed a biomechanical study to compare the augmentation of isolated fractured vertebral bodies using two different bone tamps. Compression fractures were created in 21 vertebral bodies harvested from red deer after determining their initial strength and stiffness, which was then assessed after standardised bipedicular vertebral augmentation using a balloon or an expandable polymer bone t...

Vertebral body compression fractures can cause chronic pain and may result in progressive kyphosis. Although vertebroplasty has been used to treat pain, it does not attempt to restore vertebral body height and eliminate spinal deformity. Percutaneous balloon kyphoplasty is a novel technique, which involves the introduction of inflatable bone tamps into the fractured vertebral body for elevation...

STUDY DESIGN An Institutional Review Board-approved Phase I efficacy study of inflatable bone tamp usage in the treatment of symptomatic osteoporotic compression fractures. OBJECTIVES To evaluate the safety and efficacy of inflatable bone tamp reduction and cement augmentation, "kyphoplasty," in the treatment of painful osteoporotic vertebral compression fractures. SUMMARY OF BACKGROUND DAT...

The field of evolutionary medicine examines the possibility that some diseases are the result of trade-offs made in human evolution. Spinal fractures are the most common osteoporosis-related fracture in humans, but are not observed in apes, even in cases of severe osteopenia. In humans, the development of osteoporosis is influenced by peak bone mass and strength in early adulthood as well as ag...

vertebra plana is a radiological diagnosis that indicates complete compression of the vertebral body.(1,2) this condition was reported in langerhans cell histiocytosis including eosino-philic granuloma,(3, 12) ewing's sarcoma,(2,13,14) tuberculosis,(15,16) vertebral osteomyelitis,(17) aseptic necrosis,(18) aneurysmal bone cyst,(19) osteosarcoma,(20) neuroblastoma,(21) acute leu-kemia,(22) rhabd...

AIM OF THE STUDY Different carcinomas have different characteristics, which may play a crucial role in diagnosis and treatment. Our study was aimed at understanding the development pattern of bone metastasis from hepatocellular carcinoma, based on its imaging characteristics, so as to provide a more targeted treatment. MATERIAL AND METHODS Forty two patients (123 lesions) with hepatocellular ...

Ankylosing spondylitis (AS) is inflammation of the sacroiliac joints and spine, associated with clinical symptoms such as pain stiffness in vertebral column, after which, a considerable number individuals, new bone growth occurs.

The effect of long-term treatment with the bisphosphonate zoledronate on vertebral bone architecture was investigated in estrogen-deficient mature rats. 4-month-old rats were ovariectomized and development of cancellous osteopenia was assessed after 1 year. The change of bone architectural parameters was determined with a microtomographic instrument of high resolution. After 1 year of estrogen-...