OBJECTIVE Enlargement of the lateral ventricles is among the most frequently reported macroscopic brain structural changes in schizophrenia, although variable in extent and localization. The authors investigated whether ventricular enlargement is related to regionally specific volume loss. METHOD High-resolution magnetic resonance imaging scans from 39 patients with schizophrenia were analyze...

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Background: Patients with beta-thalessemia major present with severe anemia and need continous transfusion therapy. An important complication of beta-thalessemia major is iron deposition in cardiac tissue, resulting in fibrosis and dysfunction. Cardiac involvement is the major cause of death in beta-thalessemia major. The purpose of this study was to assess cardiac disease patients with bet...

An 8-month-old Labrador retriever bitch was evaluated for sudden-onset, progressive abdominal distension. Physical examination revealed an exaggerated inspiratory effort, severe ascites, bilateral jugular vein distension, and hypokinetic femoral arterial pulses. Thoracic auscultation detected tachycardia with muffled heart sounds, without audible cardiac murmurs. Thoracic radiographs identified...

OBJECTIVE To compare correlation between right ventricular ejection fraction (RVEF) derived from MRI and equilibrium radionuclide angiocardiography (ERNA) depicted from the left anterior oblique (LAO) view and anterior (ANT) view [designated as ERNA (LAO) and ERNA (ANT), respectively]. METHODS Twenty-one patients with cardiac disorders received ERNA and cardiac MRI examination within 2 weeks ...

Thrombin and iron are two major players in intracerebral hemorrhage-induced brain injury and our recent study found that thrombin contributes to hydrocephalus development in a rat model of intraventricular hemorrhage (IVH). This study investigated the role of red blood cell (RBC) lysis and iron in hydrocephalus after IVH. There were three parts to this study. First, male Sprague-Dawley rats rec...

Severe aortic stenosis (AS) results in cardiac damages, such as left ventricular hypertrophy, atrial enlargement, pulmonary pressure elevation and advanced stage, right damage. Généreux colleagues proposed a staging classification based on these extra-valvular damages 2017, with increasing stage representing more While regression of is expected following valve replacement, the reversal damage t...