previous studies have demonstrated that vascular endothelial growth factor (vegf) can trigger angiogenesis as well as inflammation through binding to its membranous receptor-1 on endothelial and inflammatory cells. we aimed to correlate the circulatory number of cells expressing such receptor as well as the serum level of vegf and the soluble form of its receptor-1 (svegfr1) to the severity of ...

background: recently, the development of new biomarkers as prognostic and predictive markers in prostate cancer has been crucial. objectives: this study was aimed to determine whether serum vascular endothelial growth factor (vegf) levels would be a prognostic marker or risk assessment factor in patients with prostate cancer and to investigate whether it could differentiate cancerous tissue fro...

background: we investigated coronary angiogenesis and serum vascular endothelial growth factor (vegf) and its soluble receptor-1 (sflt-1) concentrations in two-kidney one-clip (2k1c) hypertensive rats before and after reversal of hypertension. methods: the animal groups were: (i) sham-clipped for 12 weeks; (ii) 2k1c for 12 weeks; (iii) sham-clipped for 12 weeks and unclipped for 12 weeks; and (...

Background: Stimulation of collateral artery growth (arteriogenesis) and/or capillary network growth (angiogenesis) would be beneficial to the patients with myocardial infarction. To understand the central role of vascular endothelial growth factor (VEGF) in biological angiogenesis, we performed molecular analysis of the VEGF gene in patients afflicted with acute myocardial infarction (AMI). Me...

the aim of this study was to investigate the response of vascular endothelial growth factor (vegf) to a bout of exhausted submaximal exercise and its correlation with vo2max in different bouts. therefore, 12 active men (mean age: 24 years) were randomly selected and performed the submaximal exercise. blood samples were collected before, immediately and two¬¬ hours after the exercise training. d...

the role of angiogenic molecules, like vascular endothelial growth factor (vegf) and fibroblast growth factor (fgf) in tumor angiogenesis was well confirmed. photodynamic therapy (pdt) action is, to very high degree, based on tumor vasculature damage. therefore, it seemed to be important to evaluate growth factor receptors after pdt. the extent of receptor expression was studied by immuno-histo...

some important compatibility that occur with exercise is increase of the capillary density or angiogenesis. vascular endothelial growth factor (vegf) have mitogen role for endothelial cells and consider an important intermediary angiogenesis process. the purpose of this study was comparing the effect of two type of physical activity on response of serum vegf-a in non-athlete men. for this aim 1...

  Background :Chronic obstructive pulmonary disease (COPD) is a third leading cause of death.   Methods : In this case control study, we prepared 5 cc bloods from the antecubital vein of 100 COPD patients and 40 healthy individuals as control group. Vascular endothelial growth factor (VEGF) expression protein level was measured by ELISA in both groups.   Results : We found that concentration of...

background: stimulation of collateral artery growth (arteriogenesis) and/or capillary network growth (angiogenesis) would be beneficial to the patients with myocardial infarction. to understand the central role of vascular endothelial growth factor (vegf) in biological angiogenesis, we performed molecular analysis of the vegf gene in patients afflicted with acute myocardial infarction (ami).   ...

During bone growth, development, and remodeling, angiogenesis as well as osteogenesis are closely associated processes, sharing some essential mediators. Vascular endothelial growth factor (VEGF) was initially recognized as the best-characterized endothelial-specific growth factor, which increased vascular permeability and angiogenesis, and it is now apparent that this cytokine regulates multip...