نتایج جستجو برای: vap
تعداد نتایج: 1805 فیلتر نتایج به سال:
BACKGROUND Ventilator-associated pneumonia (VAP) is classified as early-onset or late-onset, in part, to identify subjects at risk for infection with resistant pathogens. We assessed differences in the bacterial etiology of early-onset versus late-onset VAP. METHODS Subjects enrolled in 2004-2006 in 2 clinical studies of doripenem versus imipenem or piperacillin/tazobactam, with a diagnosis o...
CONTEXT Ventilator associated pneumonia (VAP) is a nosocomial infection prevalent among the intensive care unit (ICU) patients despite proper infection control practices. The diagnosis of VAP still remains controversial and hence the mortality rate is higher among this group of patients. AIM The aim of our study was to identify the antibiotic pattern and the appropriateness of treatment follo...
BACKGROUND Pneumonia is a common complication of hospitalisation in severely ill patients who need mechanical ventilation. The aim of this study was to assess the usefulness of the International Nosocomial Infection Control Consortium programme for the surveillance of ventilator-associated pneumonia (VAP). METHODS A prospective study (1 Jan 2012-30 June 2014) was conducted in the 20-bed ICU. ...
ALS8 is caused by a dominant mutation in an evolutionarily conserved protein, VAPB (vesicle-associated membrane protein (VAMP)-associated membrane protein B)/ALS8). We have established a fly model of ALS8 using the corresponding mutation in Drosophila VAPB (dVAP33A) and examined the effects of this mutation on VAP function using genetic and morphological analyses. By simultaneously assessing th...
background ventilator-associated pneumonia (vap) develops in mechanically ventilated patients 48 hours after putting the patients on the ventilator. vap is the second most common nosocomial infection in neonatal intensive care units (nicu). objectives the current study was conducted to determine the rate, microbiological characteristics and outcome of vap in neonates admitted in the nicu of sho...
Ventilator-associated pneumonia (VAP) is the most frequent nosocomial infection in the intensive care unit;1 between 10% and 20% of patients who receive more than 48 hours of mechanical ventilation will develop VAP.1,2 VAP is associated with prolonged hospital stay,3–5 higher cost,6 and a 2-fold higher risk of mortality.2 Prevention of VAP is essential. Recent advances in our understanding of t...
BACKGROUND Ventilator-associated pneumonia (VAP) is the most commonly fatal nosocomial infection. Clinical diagnosis of VAP remains notoriously inaccurate. The hypothesis was tested that significantly augmented inflammatory markers distinguish VAP from conditions closely mimicking VAP. METHODS A prospective, observational cohort study was carried out in two university hospital intensive care ...
OBJECTIVE To evaluate the economic impact of ventilator-associated pneumonia (VAP) on length of stay and hospital costs. Design. Retrospective matched cohort study. SETTING Premier database of hospitals in the United States. PATIENTS Eligible patients were admitted to intensive care units (ICUs), received mechanical ventilation for ≥2 calendar-days, and were discharged between October 1, 20...
Emigration of leukocytes from the blood into the tissues is critical in controlling lymphocyte patrolling in different lymphatic organs and in leukocyte accumulation at sites of inflammation. During the first stage of the extravasation process, leukocytes bind to the endothelial lining of vessels. At the molecular level, several adhesion molecules on leukocytes and endothelial cells function as...
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