OBJECTIVES When a clinical assay is stressed with extraordinarily high volume of specimens over a short period of time, extra caution may be needed to avoid systematic errors and biases. Here we report our experience with a HgbA1c assay used for high volume wellness screening purpose, to illustrate the importance of stress testing during assay validation. DESIGN AND METHODS Over 15,000 whole ...

OBJECTIVE The aim of this validation study was to assess the completeness of the registrations of chest X-rays (CXR) in two different versions of the Danish National Patient Registry (DNPR). MATERIAL AND METHODS We included electronic record data on CXR performed on patients aged 40 to 99 years from nine radiology departments covering 20 Danish hospitals. From each department, we included dat...

F or decades anatomical pathologists have established and managed diagnostic immunohistochemistry (IHC) laboratories to assist in accurate tissue diagnosis. Although test validation, quality control (QC), and quality assurance (QA) procedures have always been a part of routine operations, test results were always viewed in the context of clinical, morphological, and other IHC test results. Howe...

OBJECTIVES We evaluated whether and how the effects of risk factors on periodontal disease (PD) were modified by measurement errors using community periodontal index (CPI) and loss attachment (LA) in the community-based survey. METHODS A pilot validation study was performed to estimate the rates of false negative and false positive for both CPI and LA in 31 subjects from different regions usi...

PURPOSE While a strong learning environment is critical to medical student education, the assessment of medical school learning environments has confounded researchers. Our goal was to assess the validity and utility of the Johns Hopkins Learning Environment Scale (JHLES) for preclinical students at three Malaysian medical schools with distinct educational and institutional models. Two schools ...

Information exchange is a key factor that determines how negotiation proceeds and further what type of outcomes can be obtained from such a dynamic process. Normal information exchange includes both formal offers during the process of negotiation and informal communication occurs during or after formal negotiation. This paper examines this process using a cognitive perspective and proposes that...

Respiratory diseases, particularly allergic rhinitis, are spatially and temporally correlated with the ground PM2.5 level. A study of the correlation between the two factors should therefore account for spatiotemporal variations. Satellite observation has the advantage of wide spatial coverage over pin-point style ground-based in situ monitoring stations. Therefore, the current study used both ...

BACKGROUND Internet-based data collection relies on well-designed and validated questionnaires. The theory behind designing and validating questionnaires is well described, but few practical examples of how to approach validation are available in the literature. OBJECTIVE We aimed to validate data collected in an ongoing Internet-based longitudinal health study through direct visits to partic...

PURPOSE To validate a paper-based visual acuity (PBVA) questionnaire. METHODS In 2015, a cross-sectional survey was conducted among 301 young and middle-aged, mostly male, Japanese subjects. The participants were asked to self-rate their visual acuity (VA) on a scale from 1 to 5. Self-ratings of VA were categorized into three groups: good (1 and 2), normal (3), and poor (4 and 5). For objecti...

This article describes the development as well as the initial norming and validation of the Multifactor Measure of Performance™ (MMP™), which is a psychometric instrument that is designed to study, assess and enhance key predictors of human performance to help individuals perform at a higher level. It was created by the author, for the purpose of going beyond existing conceptual and psychometri...