نتایج جستجو برای: valacyclovir hydrochloride

تعداد نتایج: 44884  

2012
Alison L. Drake Alison C. Roxby James Kiarie Barbra A. Richardson Anna Wald Grace John-Stewart Carey Farquhar

BACKGROUND Maternal administration of the acyclovir prodrug valacyclovir is compatible with pregnancy and breastfeeding. However, the safety profile of prolonged infant and maternal exposure to acyclovir in the context of antiretrovirals (ARVs) for prevention of mother-to-child HIV-1 transmission (PMTCT) has not been described. METHODS Pregnant Kenyan women co-infected with HIV-1/HSV-2 with C...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012
E Aurelius E Franzen-Röhl M Glimåker O Akre L Grillner C Jorup-Rönström M Studahl

BACKGROUND Herpes simplex virus type 2 (HSV-2) is a common cause of acute and recurrent aseptic meningitis. Our aim was to determine the impact of antiviral suppression on recurrence of meningitis and to delineate the full spectrum of neurological complications. METHODS One hundred and one patients with acute primary or recurrent HSV-2 meningitis were assigned to placebo (n = 51) or 0.5 g of ...

2015
Shin-Yeu Ong Ha-Thi-Thu Truong Colin Phipps Diong Yeh-Ching Linn Aloysius Yew-Leng Ho Yeow-Tee Goh William Ying-Khee Hwang

BACKGROUND Valacyclovir has been used for prophylaxis against cytomegalovirus (CMV) infection after hematopoietic stem cell transplantation (HSCT). We investigated the efficacy and safety of high-dose Valacyclovir as pre-emptive therapy in patients with CMV antigenemia after HSCT. METHODS In a retrospective single center study of 61 patients, we compared the rates of viral clearance, recurren...

2012
Simon RJ Taylor Robin Hamilton Claire Y Hooper Lavnish Joshi Jiten Morarji Nitin Gupta Sue L Lightman

BACKGROUND To report the outcome of oral valacyclovir as the sole antiviral therapy for patients with acute retinal necrosis (ARN). METHODS This study reports a retrospective, interventional case series of nine consecutive patients with ten eyes with newly diagnosed ARN treated with oral valacyclovir as the sole antiviral agent. Eight patients received oral valacyclovir 2 g tid (Valtrex, Glax...

2014
Ramzia I Al-Bagary Asmaa A El-Zaher Fahima A Morsy Mai M Fouad

Aqueous alkaline degradation was performed for oseltamivir phosphate (OP) and valacyclovir hydrochloride (VA). Isocratic stability indicating the use of high-performance liquid chromatography (HPLC) was presented for each drug in the presence of its degradation product. The separations were performed using the Nucleosil ODS column and a mobile phase consisting of phosphate buffer (pH = 7), acet...

2015
Theodoros Empeslidis Vasileios Konidaris Periyasami Kumar Somnath Banerjee James Deane Konstantinos T Tsaousis

Introduction: Acute retinal necrosis (ARN) is a rare, rapidly progressive viral retinitis. The current standard of care for ARN consists of intravenous acyclovir for 5-10 days, followed by oral acyclovir for an additional 6-12 weeks. Valacyclovir has superior plasma bioavailability to acyclovir as an oral preparation. The aim of this study is to add to the evidence of treating ARN with valacycl...

Journal: :The Journal of infectious diseases 2014
Tae Joon Yi Brett Shannon Lisungu Chieza DeSheng Su Megan Saunders Wangari Tharao Sanja Huibner Robert Remis Janet Raboud Rupert Kaul

Herpes simplex virus type 2 (HSV-2) infection is associated with a 3-fold increase in the risk of human immunodeficiency virus (HIV) acquisition, perhaps through alterations in mucosal HIV-susceptible target cells. We performed a clinical trial to assess the impact of herpes therapy on cervical immunology in HSV-2-infected, HIV-uninfected women from Africa or the Caribbean who were living in To...

Journal: :The Journal of infectious diseases 1999
R A LeBlanc L Pesnicak M Godleski S E Straus

Infections by herpes simplex virus (HSV) cannot yet be eliminated, but the severity of the disease can be reduced. Two newer drugs with established efficacy for such infections, famciclovir and valacyclovir, were tested in a mouse eye model of HSV infection. Both drugs significantly reduced mortality and titers of virus shed from the eyes of mice infected with an otherwise lethal dose of HSV ty...

Journal: :In vivo 2007
A Martin Lerner Safedin H Beqaj Robert G Deeter James T Fitzgerald

BACKGROUND We hypothesized that subset classification of Epstein-Barr virus (EBV) in chronic fatigue syndrome (CFS) is required. At first, a blinded-random placebo-controlled trial of valacyclovir in EBV CFS subset was performed (Group 1), and this EBV subset was followed for thirty-six months (Group 2). Patients were given valacyclovir at 14.3 mg/kg every 6 hours. The validated Energy Index (E...

Journal: :iranian journal of pharmaceutical research 0
effat souri - aghil rahimi department of medicinal chemistry, faculty of pharmacy and pharmaceutical research center, tehran university of medical sciences, tehran (14155-6451), iran nazanin shabani ravari department of medicinal chemistry, faculty of pharmacy and pharmaceutical research center, tehran university of medical sciences, tehran (14155-6451), iran

a mixture of acetaminophen, diphenhydramine hydrochloride and pseudoephedrine hydrochloride is used for the symptomatic treatment of common cold. in this study, a derivative spectrophotometric method based on zero-crossing technique was proposed for simultaneous determination of acetaminophen, diphenhydramine hydrochloride and pseudoephedrine hydrochloride. determination of these drugs was perf...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید