Of 68,000 gynaecological cases seen during the past decade, only 25 had congenital malformations of the vaginal tract. The different types of congenital malformations, their presentation and management is presented (JPMA 36: 256, 1986).

  Introduction :Jaundice is the most common cause of hospitalization of infants in the first month of life. Delivery and maternal and neonatal risk factors may affect the progression of complications of jaundice. This study aimed to investigate the problems of pregnancy and delivery in neonates with jaundice. Methods: This descriptive study was performed on 2796 full term 3 to 29 day infants w...

We present a case of complete vaginal stenosis in a woman diagnosed with Sheehan's syndrome. The patient delivered at full-term 5 months prior, and experienced massive postpartum bleeding at that time. During evaluation of persistent amenorrhea, we found that her vaginal orifice was completely adhesive and obstructed. Prior to corrective surgery, we managed the patient with an oral contraceptiv...

Vaginal drug administration can improve prophylaxis and treatment of many conditions affecting the female reproductive tract, which includes fungal bacterial infections, sexually transmitted diseases cancer also. This is best route for proteins, peptides, also other therapeutic drugs like macro-molecules. For contraceptives, steroids, metronidazole, anti-retroviral, vaginal delivery most prefer...

The innate defense system of the female mucosal genital tract involves a close and complex interaction among the healthy vaginal microbiota, different cells, and various proteins that protect the host from pathogens. Vaginal lactobacilli and lactoferrin represent two essential actors in the vaginal environment. Lactobacilli represent the dominant bacterial species able to prevent facultative an...

During colonization of the vaginal tract Candida glabrata cells are challenged with the presence of acetic acid at a low pH, specially when dysbiosis occurs. To avoid exclusion from this niche C. glabrata cells are expected to evolve efficient adaptive responses to cope with this stress; however, these responses remain largely uncharacterized, especially in vaginal strains. In this work a cohor...

BACKGROUND Cervical ripening during pregnancy resembles an inflammatory process. Matrix metalloproteinases (MMPs), particularly MMP-8, have been linked to inflammatory processes. We studied the concentrations of, and factors associated with, MMP-8 in the lower genital tract fluids in the first and second trimesters. METHODS In a prospective population-based cohort study, vaginal and cervical ...

Lactic acid at sufficiently acidic pH is a potent microbicide, and lactic acid produced by vaginal lactobacilli may help protect against reproductive tract infections. However, previous observations likely underestimated healthy vaginal acidity and total lactate concentration since they failed to exclude women without a lactobacillus-dominated vaginal microbiota, and also did not account for th...

This study aims to determine the prevalence self-reported abnormal vaginal discharge and to identify associated risk factors in pregnant women in the municipality of Rio Grande, Rio Grande do Sul State, Brazil. A standardized questionnaire was applied to all pregnant women admitted for delivery in local maternity hospitals. The chi-square test was used to compare proportions, and Poisson regres...