It is well known that the phosphatase and tensin homolog deleted from chromosome 10 (Pten) is a tumor suppressor and is indispensable for epithelial cell homeostasis to prevent tumor formation. Mutations in Pten are frequently found both in sporadic and hereditary cancers, and mice with Pten deletion and/or loss-offunction mutations are highly susceptible to tumor induction by aberrant phosphat...

Gartner’s cyst accounts for 11% of all vaginal cysts. It results from total or partial occlusion duct, the mesonephric duct remainder. is often located in anterior lateral wall vagina cervix to introitus, however it has exceptionally been described posterior location also.It typically small and asymptomatic occurs along walls vagina, following course duct. Rarely can be congenital., ,

Elucidating the cellular and molecular mechanisms regulating sperm selection and transport in the vagina of the hen had been the focus of a limited amount of research over the past decade. New observations indicate the presence of nonneuron endocrine cells in the epithelia lining the lumina of the turkey hen vagina and uterovaginal junction. Although no cells in the vagina or uterovaginal junct...

In a female child presenting with vaginal bleeding or a mass protruding through the vagina, it is mandatory to perform an endoscopic and laparoscopic examination and biopsy to establish the correct diagnosis and precise extent of the lesion. An endodermal sinus tumor (EST) of the vagina is a rare, malignant germ cell tumor that occurs primarily in infants. Clearly, the vagina is a critical site...

Malignant melanoma (MM) of the vagina is a rare tumor. It accounts for less than 1% of all MM, and less than 3% of all primary malignant tumors of the vagina (1). In a review of reported cases, Stellato et al. (2) found less than 150 cases of primary melanoma of the vagina in the literature. The histologic appearance of melanoma may be heterogeneous. In fact, especially amelanotic melanomas may...