AIMS To analyze the prognostic role of antinuclear antibodies (ANA) for the onset of uveitis in the context of juvenile idiopathic arthritis (JIA), its correlation with uveitis course and severity and its prognostic role for the development of arthritis in children with uveitis. METHODS We conducted a systematic review analysis of the literature on the prognostic value of ANA on JIA associate...

BACKGROUND Typically juvenile idiopathic arthritis (JIA)-associated uveitis (further referred as 'JIA-uveitis') has its onset in childhood, but some patients suffer its, sometimes visual threatening, complications or ongoing disease activity in adulthood. The objective of this study was to analyze uveitis activity, complications and visual prognosis in adulthood. METHODS In this multicenter s...

Uveitis or intraocular inflammation is a potentially blinding disorder that is initiated by a diverse group of diseases. Concepts of uveitis have evolved rapidly over the past few years, but many questions about the aetiology still remain unanswered. Uveitis is associated with several systemic diseases but the frequency of systemic diseases among uveitis patients is dependent on age of onset an...

The inflammatory process of the uvea is called uveitis and may cause sight threatening damage to the eye. The aetiological factor in about 30% of the cases of uveitis is unknown. If established clinical entities without known cause, such as Fuchs' uveitis, are included, no aetiological agent or association with systemic disease can be identified in about 50% of cases.' Uveitis may be induced by...

A distinct clinical entity of uveitis associated with human T lymphotropic virus type 1 (HTLV-I) has been reported previously. During the period between January 1989 and April 1992, 93 patients were observed with HTLV-I uveitis and a significant correlation was found between Graves' disease and HTLV-I uveitis. Sixteen of the 93 patients with HTLV-I uveitis (17.2%) had a previous history of Grav...

OBJECTIVE To determine the prevalence of uveitis in patients with recent inflammatory back pain (IBP) suggestive of spondylarthritis (SpA), and to investigate the impact of uveitis on the overall features of these patients. METHODS The Devenir des Spondylarthropathies Indifférenciées Récentes (DESIR; Outcome of Recent Undifferentiated Spondylarthropathies) cohort is a prospective multicenter ...

PURPOSE This study was conducted to determine the incidence of luetic uveitis in the last seven years at our uveitis center and to describe the characteristics and the role of uveitis in the diagnosis of syphilitic infection with or without unknown HIV infection. METHODS We retrospectively reviewed syphilitic uveitis in patients observed at our center between 2004 and 2010. The diagnosis was ...

AIMS/BACKGROUND Anterior uveitis associated with juvenile chronic arthritis concerns two different clinical entities: firstly, antinuclear antibody (ANA) positive patients who have a chronic anterior uveitis with severe complications and often a poor visual prognosis; secondly, usually HLA-B27 positive children, predominantly boys, with unilateral recurrent anterior uveitis. Three patients are ...

Antihistone antibodies (AHAs) as measured by an enzyme linked immunosorbent assay (ELISA) were detected in the sera of 58 (48%) of 121 unselected patients with juvenile chronic arthritis (JCA). AHAs were found in 28 (93%) of 30 patients with JCA with uveitis but in only 30 (33%) of 91 patients with JCA without uveitis. AHA positivity was unrelated to the type of joint involvement, disease activ...

BACKGROUND Endogenous uveitis has long been considered to be uncommon in elderly patients. Recently, population-based studies have shown an increase in the incidence of uveitis with inreasing age. It was the aim of this study to analyse the age distribution of patients presenting with endogenous uveitis in the setting of an eye centre. METHODS Retrospective cohort analysis. RESULTS 278 pati...