UNLABELLED Uterine artery adaptations during gestation facilitate increases in uterine blood flow and fetal growth. HYPOTHESIS local expression and distribution of uterine artery connexins play roles in mediating in vivo gestational eNOS activation and NO production. We established an ovine model restricting pregnancy to a single uterine horn and measured uterine blood flow, uterine artery sh...

Uterine vascular tone significantly decreases whereas uterine blood flow dramatically increases during pregnancy. However, the complete molecular mechanisms remain elusive. We hypothesized that increased Ca -activated K (BKCa) channel activity contributes to the decreased myogenic tone of uterine arteries in pregnancy. Resistance-sized uterine arteries were isolated from nonpregnant and near-te...

Post-partum haemorrhage is a major determinant of maternal mortality. Traditionally, cases of post-partum haemorrhage caused by arterial injuries were managed by caesarean hysterectomies or bilateral internal iliac artery ligations. The diagnosis of aneurysms or arteriovenous malformations of uterine artery are often missed. Uterine curettage, caesarean section or vaginal delivery can result in...

background: congenital uterine malformations are the result of disturbances in mullerian duct development. in patients with recurrent miscarriage, the reported frequency of uterine anomalies varies widely, from 1.8% to 37.6%. there are reports in which cervical cerclage has been shown to prevent preterm labor in uterine anomalies. the aim of this study was to compare the role of cervical cercla...

this is a case-control study. the purpose was to investigate for risk factors for cystocele, rectocele, and uterine prolapsed in women. the sample was 249 women who refereed to a gynecological clinic. of them 155 women placed in case and 84 women placed in control group. the tool for data gathering was a questionnaire which was designed in three parts. the first part was demographic characteris...

background uterine artery embolization (uae) is a minimally invasive procedure performed under fluoroscopy for the treatment of uterine fibroids and accompanied by radiation exposure. objectives to compare ovarian radiation doses during uterine artery embolization (uae) in patients using conventional digital subtraction angiography (dsa) with those using digital flat-panel technology. patients ...

background: there is much debate about effects of medicinal plants such as saffron (crocus sativus) on human health. women are highly involved in farming and processing of this plant. this study is aimed at evaluating the saffron impacts on miscarriage rate of female farmers working in saffron fields. methods: this was a prospective case-control study on pregnant female farmers during harvestin...

background: worldwide, cervical cancer is one of the most challenging gynecologic cancers in treatment. objectives: this study was designed with the aim of comparing patients treated with external beam radiotherapy (ebrt) and interactivity brachytherapy (icbt) with ebrt and extrafascial hysterectomy in locally advanced stages of cervical cancer (iib-iii). patients and methods: the present study...

Uterine vascular tone significantly decreases whereas uterine blood flow dramatically increases during pregnancy. However, the complete molecular mechanisms remain elusive. We hypothesized that increased Ca(2+)-activated K(+) (BK(Ca)) channel activity contributes to the decreased myogenic tone of uterine arteries in pregnancy. Resistance-sized uterine arteries were isolated from nonpregnant and...

Spontaneous uterine rupture is a life-threatening obstetrical emergency carrying a high risk for the mother and the fetus. Spontaneous uterine rupture in early pregnancy is very rare complication and it occurs usually in scarred uterus. Uterine anomalies are one of the reasons for spontaneous unscarred uterine rupture in early pregnancy. Obstetricians must consider this diagnosis when a pregnan...