OBJECTIVE These studies were undertaken to characterize the subcellular localization of the two major isoforms of progesterone receptors (PR), PRA and PRB, in endometrial cancer. METHODS Immunohistochemistry, immunoprecipitation, and confocal microscopy were performed using Hec50co and KLE endometrial cancer cell models expressing PRA or PRB as a consequence of transduction. The location of P...

OBJECTIVE To test the hypothesis that the blood antithrombin (AT) activity is correlated with the plasma aldosterone concentration (PAC), the plasma renin activity (PRA), and/or the PAC-to-PRA ratio during the late stage of pregnancy. METHODS The AT activity, PAC, and PRA were determined within 7 days prior to delivery in 47 women, consisting of 30 normotensive and 6 hypertensive women with s...

BACKGROUND The immune monitoring of islet transplant recipients includes the assessment of panel reactive antibodies (PRA). A negative association of PRA+ with allogeneic solid organ graft survival has been recognized, but scattered data is available for islet transplantation. METHODS We performed a retrospective analysis of PRA status in 66 patients with type 1 diabetes mellitus recipient of...

BACKGROUND A plasma renin activity (PRA)-guided strategy is more effective than standard care in treating hypertension (HTN). However, its clinical implementation has been slow, presumably due in part to economic concerns. We estimated the cost effectiveness of a PRA-guided treatment strategy compared with standard care in a treated but uncontrolled HTN population. METHODS We estimated costs,...

BACKGROUND The measurement of renin activity is complicated by difficulties in the quantification of angiotensin 1 (Ang1), the product of the renin-catalyzed reaction. We report an HPLC-electrospray-tandem mass spectrometry (HPLC-ESI-MS/MS) method for the quantification of Ang1 as a measure of plasma renin activity (PRA). METHODS After incubation (37 degrees C for 3 or 18 h), samples were pre...

This study aims to determine the potential, problems and problem solving in Nagari Talang. In this research, data collection used Participatory Rural Appraisal (PRA) method, while analysis SWOT method. The PRA techniques were Trend Charting LivelihoodChanges, Institutional Studies (Venn Diagrams), Daily Activity Charts Village Transects. results of show potential village form land area, beautif...

Abstract. Daris L, Massiseng ANA, Fachry ME, Jaya, Zaenab ST. 2022. The impact of fishermen’s conflict on the sustainability crab (Portunus pelagicus) resources in coastal areas Maros District, South Sulawesi, Indonesia. Biodiversitas 23: 5278-5289. Using environmentally unfriendly fishing gear causes damage to coral reefs and seagrass, which are habitat crabs. prohibition using ecologically ge...

Objective Percutaneous transluminal renal artery angioplasty (PTRA) has been recommended for the treatment of renovascular resistant hypertension. However, large randomized trials have reported that PTRA did not improve the outcomes compared with optimal medical therapy in patients with renal artery stenosis (RAS). It is important to identify patients with renovascular hypertension who are like...

Critical knowledge gaps seriously hinder efforts for building disaster resilience at all levels, especially in disaster-prone least developed countries. Information deficiency is most serious at local levels, especially in terms of spatial information on risk, resources, and capacities of communities. To tackle this challenge, we develop a general methodological approach that integrates communi...