A 61-year-old woman with a remote history of renal transplant was admitted for evaluation of weakness and intermittent cough for the past 3 months and pulsating headache for 1 month. She had diarrhea for several years. She denied experiencing fever, night sweats, or weight loss. She was on tacrolimus/mycophenolate/ prednisone and ciprofloxacin. She had diffuse lymphadenopathy/splenomegaly and a...

Little did Christian Gram1 know that his differential staining technique developed in 1884 would remain one of the first procedures learned by beginning bacteriology students and one of the first procedures carried out in any laboratory where bacteria are routinely identified at the end of the 20th century. In today's high-tech medical world where the utilization of nucleic-acid amplification i...

OBJECTIVE To establish a polymerase chain reaction (PCR) assay for the rapid detection and identification of mycobacteria in urine, and to assess the value of such assay in routine laboratory diagnosis of genitourinary tuberculosis. MATERIALS AND METHODS Urine specimens from 1000 patients with clinical suspicion of urinary tuberculosis were examined. Two assays for the detection and identific...

PURPOSE Urinary stasis is a risk factor for recurrent urinary tract infection (UTI). Homozygous mutant Megabladder (Mgb-/-) mice exhibit incomplete bladder emptying as a consequence of congenital detrusor aplasia. We hypothesize that this predisposes Mgb-/- mice to spontaneous and experimental UTI. METHODS Mgb-/-, Mgb+/-, and wild-type female mice underwent serial ultrasound and urine culture...

Primary systemic amyloidosis is a rare entity. We report a case of primary systemic amyloidosis without any associated hematological abnormality who presented with macroglossia and hemorrhagic lesions around eyes and sub mammary region. There were soft lobulated masses around perianal region, labia majora and on external auditory meatus obstructing auditory canal. She was also operated for carp...

Tuberculosis of the penis is rare. The clinical features of penile tuberculosis are usually manifested as ulceration or scars. However, the authors encountered a case of penile tuberculosis that presented as a mass. A painless nodule at the base of the penis was noted in a 63-year-old male patient. Surgical excision was recommended, and pathologic finding revealed granulomatous inflammation in ...