Communications by Harris et al. (1, 2), Johnson and Zilva (3), van Eekelen (4), Hawley et al. (5), and Youmans et al. (6) have established the relationship of the output of vitamin C in the urine to the nutritional state of the organism with respect to this vitamin. They have shown that subjects maintained on diets inadequate in their vitamin C content, excrete only traces of ascorbic acid in t...

Submitted June 18, 2014; revision received July 17, 2014; accepted July 31, 2014. computed tomography images in patients with elevated serum creatinine concentrations.1,2 Urinary output without proper catheter positioning can persist if the catheter tip is located beyond the membranous external urethral sphincter.3 The patency and proper placement of urinary catheters should be confirmed in the...

The relationship between urinary excretion of porphyrins, porphyrin precursors and total oestrogens in normal pregnancy was investigated. Significant increases in total oestrogen, delta-aminolaevulinic acid (ALA) and coproporphyrin (COPRO) excretion were noted. However, no close correlation was found between total oestrogen excretion and urinary output of ALA and COPRO. The results suggest that...

I N Central Anuenicam as in Jamaica2 and Africa,3 childre suffering from the severe protein dleficiency of kwashiorkor have been found to have a very low urinary output of creatinine. Standlard et al. found that during recovery urinary creatinine increases proportionally to the increase in muscle mass. However, about half of their patiemits and most of ours showedi an abrupt transient rise in c...

Aquaporin-2 (AQP-2), a water channel located on the apical membrane of collecting duct cells, regulates water reabsorption under the control of vasopressin (AVP). Using an antibody directed to human AQP-2, a quantitative Western blot analysis was performed to determine the collecting duct responsiveness to an oral, nonpeptide, V2 receptor antagonist (VPA-985) in patients with chronic NYHA II an...

Nitrite-treated meat is a reported risk factor for colon cancer. Mice that ingested sodium nitrite (NaNO2) or hot dogs (a nitrite-treated product) showed increased fecal excretion of apparent N-nitroso compounds (ANC). Here, we investigated for the first time whether rats excrete increased amounts of ANC in their urine after they are fed NaNO2 and/or hot dogs. Rats were treated for 7 days with ...

The use of urinary and/or biliary excretion data was considered as an alternative approach if the bioanalytical method lacked the appropriate sensitivity to adequately characterize the serum or plasma concentration-time profile. This approach is used for the analysis of plasma concentration-time profile under the lower limit of quantification (LLOQ) of various analytical instruments. The object...

Thirteen patients with ileopathy were studied under metabolic ward conditions, first on a 100-g fat diet and later on a 40-g fat diet. Ten of the patients were studied after three to 27 months on a fat-reduced diet. Ten of the patients had a high urinary oxalate excretion on the high-fat diet compared with a control group. The patients with a faecal fat output of more than 15 g a day showed a r...