BackgroundTicagrelor is a reversible oral P2Y12 platelet inhibitor used to treat patients with acute coronary syndromes, prior myocardial infarction, high-risk artery disease, transient ischemic attack, or stroke. A healthy volunteer study showed that the intravenous monoclonal antibody bentracimab rapidly reverses ticagrelor, but effect in was unknown.MethodsIn prespecified interim analysis of...

Urgent urologic interventions create a challenging scenario when they occur in patients suffering from concurrent acute coronary syndrome. Herewith we report two with this scenario. Case 1, male patient was admitted non-ST elevation myocardial infarction which dual antiplatelet therapy initiated. He developed symptomatic right obstructive uropathy. 2, and commenced on therapy. Subsequently, he ...

OBJECTIVES To assess perceptions of the informed consent process in patients undergoing urgent abdominal surgery. DESIGN A prospective observational study was carried out using structured questionnaire-based interviews. Patients who had undergone urgent abdominal surgery were interviewed in the postoperative period to ascertain their perceptions of the informed consent process. Replies were c...

OBJECTIVE To estimate the ability of parents to recall the injuries of their children. DESIGN Comparison of parent recall with computerized medical records. SETTING A health maintenance organization in Washington State during 2003. SUBJECTS Parents of children younger than 6 years. MAIN OUTCOME MEASURES The ratio of recalled injuries to injuries in computerized data. RESULTS Telephone...

objective the purpose of this study was to assess the frequency of complications of endotracheal intubation (eti) in neonates. methods the newborns that were admitted and needed urgent or semi-urgent intubation were enrolled in this study over a 1 year period. route for intubation in all cases were orotracheal. cases were not routinely sedated or paralyzed. the patients were clinically and radi...

BACKGROUND Ulcerative colitis (UC) is known as an immune disorder of the colon that generally involves the rectum, but an atypical distribution of inflamed mucosa has previously been noted in certain subtypes of UC, such as the rectal-sparing type (RST). As noted in a previous report, patients with the RST may be at elevated risk for disease refractoriness, but the clinical significance of RST ...

BACKGROUND Urgent referral for suspected cancer was implemented in Denmark on 1 April 2008 to reduce the secondary care interval (i.e. the time interval from the general practitioner's first referral of a patient to secondary health care until treatment is initiated). However, knowledge about the association between the secondary care interval and urgent referral remains scarce. The aim of this...

BACKGROUND/AIMS This study was performed to investigate the clinical role of urgent esophagogastroduodenoscopy (EGD) for acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) performed by experienced endoscopists after hours. METHODS A retrospective analysis was performed for consecutively collected data of patients with ANVUGIB between January 2009 and December 2010. RESULTS A total ...