نتایج جستجو برای: urea transporter b expression

تعداد نتایج: 1715338  

2012
Susanne Grether-Beck Ingo Felsner Heidi Brenden Zippora Kohne Marc Majora Alessandra Marini Thomas Jaenicke Marina Rodriguez-Martin Carles Trullas Melanie Hupe Peter M. Elias Jean Krutmann

Urea is an endogenous metabolite, known to enhance stratum corneum hydration. Yet, topical urea anecdotally also improves permeability barrier function, and it appears to exhibit antimicrobial activity. Hence, we hypothesized that urea is not merely a passive metabolite, but a small-molecule regulator of epidermal structure and function. In 21 human volunteers, topical urea improved barrier fun...

Journal: :American journal of physiology. Renal physiology 2001
S M Bagnasco T Peng M G Janech A Karakashian J M Sands

We have isolated and characterized the human homolog of the rat largest urea transporter of the UT-A family (hUT-A1). The 4.2-kb hUT-A1 cDNA encodes a 920-amino acid peptide, which is 89% identical to the rat UT-A1 protein. By Northern hybridization, hUT-A1 expression is detected in the human inner medulla as a approximately 4.4-kb mRNA transcript. By Western analysis, hUT-A1 is identified as a...

Journal: :Journal of the American Society of Nephrology 1998

2015
Baoxue Yang

Urea transporter (UT) proteins, including isoforms of UT-A in kidney tubule epithelia and UT-B in vasa recta endothelia and erythrocytes, play an important role in the urine concentration mechanism by mediated an intra renal urea recycling, suggesting that functional inhibition of these proteins could have therapeutic use as a novel class of diuretic. Recently several classes of UT inhibitors h...

Journal: :Revista Brasileira De Fruticultura 2023

Abstract The management of organic fertilization in passion fruit has been carried out empirically based on the responses crops and experience farmers. Knowledge physiological plants to fertilizers is essential optimize programs. objective this study was evaluate differential expression genes coding for nitrate transporters as well plasma membrane H+-ATPase seedlings treated with different pres...

Journal: :The Journal of experimental biology 2015
Christophe M R LeMoine Patrick J Walsh

In the two decades since the first cloning of the mammalian kidney urea transporter (UT-A), UT genes have been identified in a plethora of organisms, ranging from single-celled bacteria to metazoans. In this review, focusing mainly on vertebrates, we first reiterate the multiple catabolic and anabolic pathways that produce urea, then we reconstruct the phylogenetic history of UTs, and finally w...

Journal: :Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2010
W Gary Anderson Patricia J Dasiewicz Suadi Liban Calen Ryan Josi R Taylor Martin Grosell Dirk Weihrauch

The present study reports aspects of GI tract physiology in the white-spotted bamboo shark, Chiloscyllium plagiosum, little skate, Leucoraja erinacea and the clear nose skate, Raja eglanteria. Plasma and stomach fluid osmolality and solute values were comparable between species, and stomach pH was low in all species (2.2 to 3.4) suggesting these elasmobranchs may maintain a consistently low sto...

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