BACKGROUND/AIMS To explore clinical patterns, predisposing factors, psychosocial aspects and the possible pathogenesis in Functional Vomiting (FV) patients. METHODS Ten healthy subjects and 19 FV patients participated in this study. Gastrointestinal symptoms and psychological state were evaluated by questionnaires, including Zung self-rating anxiety and depression scale and Eysenck personalit...

Foamy viruses (FVs) are classified in the family Retroviridae, but recent data have shown that they are not conventional retroviruses. Notably, several characteristics of their particle replication strategies are more similar to those of hepatitis B virus (HBV) than those of typical retroviruses. Compared to conventional retroviruses, which require only Gag proteins for budding and release of v...

Based on advances in acquisition, storage, and dissemination technology, increasing amounts of multimedia content such as images, audio, video, or 3D models, become available. The Feature Vector (FV) paradigm is one of the most popular approaches for managing multimedia content due to its simplicity and generality. It maps multimedia elements from object space to metric space, allowing to infer...

The two murine retroviral restriction genes, Fv-4 and Akvr-1, are very similar in their effects, distributions, ranges of action, and phenotypes. Akvr-1 has been shown to segregate independently in backcrosses with a variety of retroviral restriction loci, including Fv-1, Fv-2, Ril-1, and Ril-2. An allelism test cross of FRG (Fv-4R) X LCRR (Akvr-1R) hybrids mated to AKR mice failed to produce a...

Activated protein C (APC) inhibits coagulation by cleaving and inactivating procoagulant factor Va (FVa) and factor VIIIa (FVIIIa). FV, in addition to being the precursor of FVa, has anticoagulant properties; functioning in synergy with protein S as a cofactor of APC in the inhibition of the FVIIIa-factor IXa (FIXa) complex. FV:Q506 isolated from an individual homozygous for APC-resistance is l...

Multiple host genes have been shown to influence the course of erythroleukemia induced by Friend virus (FV) 1 (1). Two H-2-associated genes and a non-H-2-1inked gene are required for recovery from FV leukemia (2, 3). The non-H-2-1inked gene, Rfv-3, appears to influence the production of anti-FV antibody independent of the H-2 genotype (3). Although mice of the Rfv-3 r/~ genotype produce high le...

Activated protein C (APC) inhibits coagulation by cleaving and inactivating procoagulant factor Va (FVa) and factor VIIIa (FVIIIa). FV, in addition to being the precursor of FVa, has anticoagulant properties; functioning in synergy with protein S as a cofactor of APC in the inhibition of the FVIIIafactor IXa (FIXa) complex. FV:Q506 isolated from an individual homozygous for APC-resistance is le...

Fv-4 is a mouse gene that dominantly confers resistance to infection with Friend murine leukemia virus (F-MuLV) (S. Suzuki, Jpn. J. Exp. Med. 45:473-478, 1975). However, the resistance caused by Fv-4 is recessive in nude mice, which suggests that immunological effects play important roles in this resistance in vivo (K. Higo, Y. Kubo, Y. Iwatani, T. Ono, M. Maeda, H. Hiai, T. Masuda, K. Kuribaya...

Foamy virus (FV) vectors are promising tools for gene therapy, but low titer is a major challenge for large-scale clinical trials. Here, we increased FV vector titer 50-fold by constructing novel vector plasmids and using polyethylenimine-mediated transfection. FV and lentiviral (LV) vectors were used separately to transduce human CD34(+) cells at multiplicities of infection of 25, and those ce...

generation at the activated platelet surface. What remains uncertain, however, is whether residual platelet FV levels correlate with the severity of bleeding in severe FV-deficient patients. Although there has been speculation on this correlation,8 no systematic study has been done. Furthermore, mechanistic studies are needed to investigate some remaining questions. The first relates to the ori...