Objective: To study the incidence, clinical profile & HLA association of subsets of spondyloarthritis patients in eastern India. Results: Ankylosing spondylitis(AS) constitutes maximum number of cases followed by undifferentiated spondyloarthropathy(USpA) and others. 59% of AS cases presented with both axial & peripheral arthritis whereas 41% have only axial presentation. Reactive arthritis (Re...

C reactive protein (CRP) and immunoglobulin G (IgG) were measured in synovial fluid and serum of 72 patients (29 with rheumatoid arthritis (RA), 17 with osteoarthritis, 11 with crystal synovitis, seven with undifferentiated arthritis, and eight with seronegative arthritis). The synovial fluid:serum (SF:S) ratios were compared with those calculated from the SF:S ratios of transferrin, caerulopla...

Methods All patients seen in study centers between 1983 and 2004 (N = 750) were classified according to ILAR criteria. Categories of systemic arthritis, RF-positive polyarthritis, and enthesitis related arthritis were excluded because it was felt they represent sufficiently homogeneous entities. Patients in the remaining categories (oligoarthritis persistent and extended, RF-negative polyarthri...

Globally, incidence of HIV is on the rise. The epidemic of HIV infection has also affected the practice of rheumatologists. The increased life span of patients with HIV disease has resulted in emergence of musculoskeletal impairments ranging widely from arthritis to traumatic fractures. Joint disorders are common during the course of HIV infection. They are more prevalent in the late stages of ...

OBJECTIVE To evaluate the diagnostic properties and predictive value of the second generation of anti-CCP antibodies (anti-CCP2) in rheumatoid arthritis (RA) patients. METHODS A systematic review of the published literature between January 2002 and June 2005 was performed. Data were extracted regarding the sensitivity and specificity of anti-CCP2 antibodies in making an accurate diagnosis of ...

stem cells are self-renewing and undifferentiated cell types that can be differentiate into functional cells. stem cells can be classified into two main types based on their source of origin: embryonic and adult stem cells. stem cells also classified based on the range of differentiation potentials into totipotent, pluripotent, multipotent, and unipotent. multipotent stem cells have the ability...

Objective:Undifferentiated inflammatory arthritis is one of the requirements for being diagnosed in patient doesnt meet classical criteria recognized arthritis. which no approved treatment algorithm exist. Sulfasalazine and hydroxychloroquine used this trial early Undifferentiated Methods: A six-month, double-blind, randomized experiment was conducted. 100 consecutive patients. ESR, morning sti...

Background and Aims GM-CSF-dependent macrophage polarization has been demonstrated in rheumatoid arthritis (RA). Our aim was to seek diagnostic/prognostic biomarkers for undifferentiated (UA) by analyzing GM-CSF expression source, density joints of patients with UA evolving RA or PsA compared established PsA, respectively. Methods Synovial tissue (ST) from (UA>RA, n=8), (UA>PsA, n...