Melinjo (Gnetum gnemon L.) seed extract (MSE) containing trans-resveratrol (3,5,4'-trihydroxy-trans-stilbene) and other derivatives exerts various beneficial effects. However, its mechanism of action in humans remains unknown. In this study, we aimed to investigate beneficial effects of MSE in healthy adult males. In this double-blind, randomized controlled study, 30 males aged 35-70 years with...

Abstruct-Rate of convergence results are established for vector quantization. Convergence rates are given for an increasing vector dimension and/or an increasing training set size. In particular, the following results are shown for memoryless realvalued sources with bounded support at transmission rate R: (1) If a vector quantizer with fixed dimension k is designed to minimize the empirical mea...

Aims and method To investigate medical students' performance at and perceptions of the mental state examination (MSE) at a medical school with a modern integrated curriculum. We undertook an evaluative case study comprising a survey and analysis of performance data. The study is presented in two parts: part 1 discusses the students' perceptions of the MSE and the teaching, learning and practisi...

In this paper, a relationship between Linear Discriminant Analysis (LDA) and the generalized Minimum Squared Error (MSE) solution is presented. The generalized MSE solution is shown to be equivalent to applying a certain classification rule in the space defined by LDA. The relationship between the MSE solution and Fisher Discriminant Analysis (FDA) is extended to multi-class problems and also t...

Objectives: (1) To understand what hardness is, and how it can be used to determine material properties. (2) To conduct typical engineering hardness tests and be able to recognize commonly used hardness scales and numbers. (3) To be able to understand the correlation between hardness numbers and the properties of materials (4) To learn the advantages and limitations of the common hardness test ...

—We address the problem of linear minimum meansquared error (LMMSE) estimation under constraints on the lter or the estimated signal. We develop a general formula that leads to closed form solutions for a wide class of constrained LMMSE problems. The results are applicable to both nite dimensional problems as well as to the Wiener ltering setup, in which in nitely-many measurements are availabl...

We study biased control variates (BCVs), whose purpose is to improve the efficiency of stochastic simulation experiments. BCVs replace the control-simulation mean with an approximation; the resulting control-variate estimator is biased. This bias may not be a significant issue for finite sample sizes, however, because our estimator minimizes the more general mean-squared-error (mse), i.e., the ...

Parameters of glucose dynamics recorded by the continuous glucose monitoring system (CGMS) could help in the control of glycemic fluctuations, which is important in diabetes management. Multiscale entropy (MSE) analysis has recently been developed to measure the complexity of physical and physiological time sequences. A reduced MSE complexity index indicates the increased repetition patterns of...