OBJECTIVE Tissue engineering of viable, autologous cardiovascular replacements with the potential to grow, repair and remodel represents an attractive approach to overcome the shortcomings of available replacements for the repair of congenital cardiac defects. Currently, vascular myofibroblast cells represent an established cell source for cardiovascular tissue engineering. Cell isolation requi...

objective oxygen intoxication plays an important role in the pathogenesis of some fetal diseases such as encephalopathy, ischemia& hypoxia. antioxidants can reduce oxidative damage in newborns. the object of this research was measuring total value of antioxidant and vitamin c in blood sample of pregnant women before delivery, and also in umbilical cord blood of their newborn, and repeating thes...

background: brain hypoxia-ischemia is a human neonatal injury that is considered a candidate for stem cell therapy. methods: the possible therapeutic potential of human umbilical cord blood (hucb) stem cells was evaluated in 14-day-old rats subjected to the right common carotid occlusion, a model of neonatal brain hypoxia-ischemia. seven days after hypoxia-ischemia, rats received either saline ...

background: considering the increasing rates of early hospital discharge and kernicterus in healthy full term newborns, timely identification of neonates at risk of severe hyperbilirubinemia is of great significance. the aim of this study was to investigate the predictive value of umbilical cord serum (ucs) bilirubin level for subsequent hyperbilirubinemia. moreover, we compared the predictive ...

introduction the increase in the use of breast feeding and the decrease in mothers' hospitalization in the past few years have caused  an increase in the infant bilirubin level, so it is necessary to introduce methods which can identify infants with higher risks of hyperbiliru binemia. the aim of this study is to determine the predictive value of measuring the umbilical cord bilirubin for ...

conclusions changes in neonatal leptin levels can reflect changes in the body fat tissue and neonatal birth weight and could be effective in predicting weight gain in newborns with mothers who have gestational diabetes and may reduce birth trauma or future complications. results serum leptin levels in the cord blood of mothers with gdm were significantly higher than in normal mothers. there was...

BACKGROUND It is evident that infant's umbilical cord is essential for its survival and growth. In the past, it was not considered as a necessary tissue. However, nowadays, it has attracted lots of attention and its relation to different diseases has been demonstrated. In Iranian traditional medicine, caring for newborn's umbilical cord has been frequently recommended and it has been associated...

Mesenchymal stromal cells (MSCs) are multipotent cells that can give rise to different cell types of the mesodermal lineages. They are powerful sources for cell therapy in regenerative medicine as they can be isolated from various tissues, and can be expanded and induced to differentiate into multiple lineages. Recently, the umbilical cord has been suggested as an alternative source of MSCs. Al...