The present study was undertaken to investigate the mechanism of cytoprotective effects of magaldrate in aspirin plus pylorus-ligation model and ethanol-induced gastric ulcer model in rats. Magaldrate (60 mg/kg, p.o.) produced a significant reduction in the ulcer index and significant increase in mucus content in ethanol-induced gastric ulceration in rats. In aspirin plus pylorus-ligation model...

BACKGROUND & AIMS There is controversy over whether psychological stress contributes to development of peptic ulcers. We collected data on features of life stress and ulcer risk factors from a defined population in Denmark and compared these with findings of confirmed ulcers during the next 11-12 years. METHODS We collected blood samples and psychological, social, behavioral, and medical data...

Background & Aim:  Ulcer index is one of the most common diseases among people. Current therapies include acid secretion inhibitors which have various side effects. Herbal medicines are considered as adjuvant therapy for this disease. Hydroalcoholic extract of Thymus daenensis has various components such as flavonoids which contribute to gastroprotection. Experimental: 35 <em...

The herbal medicines derived from various plants extracts are being increasingly utilized to treat a wide variety of clinical diseases 1 . Besides their action as gastroprotectives, flavonoids also act in healing of gastric ulcers 2 . The study was designed to investigate the anti-ulcer effect of chloroform extract of Chrozophora plicata leaves (600mg/kg) against experimentally induced ulcer mo...

OBJECTIVE Most of the literature about Curling's ulcer was published from 1960 through 1980. Therefore, an updated study of Curling's ulcer is needed. We analyzed the risk factors affecting ulcer incidence in burn patients. METHODS We retrospectively analyzed the medical records of burn patients who were admitted to two burn centers. We collected information about the general characteristics ...

Peptic ulcer is common in present days due to stress and anxiety. Peptic ulcer is thought to result from an imbalance between acid-pepsin secretion and mucosal defense factors. Though currently available drugs provide adequate relief from pain, promote healing, the problem of relapse has eluded success. The present study was designed to evaluate the combination effect of melatonin with lansopra...

In this study ethanolic extract of Aegle marmelos was evaluated for its anti-ulcer activity against aspirininduced gastric ulcer in albino rats. Various biochemical parameters such as gastric volume, pH of gastric content, free acidity and total acidity, total carbohydrate content such as total protein, hexoses, hexosamine, fucose and sialic acid were estimated in alcoholic precipitate of gastr...

Marjolin’s ulcer is an uncommon malignant condition related to non-healing wounds, more often of burn injuries. Our aim is increase the suspicion index of primary care workers about the risk of squamous cell carcinoma in skin chronic ulcers or scar tissue, mainly in extremities. We report a Marjolin’s ulcer associated with traumatic chronic ulcer in the leg of a 73-year-old white female. Histol...

background &amp; aim:  ulcer index is one of the most common diseases among people. current therapies include acid secretion inhibitors which have various side effects. herbal medicines are considered as adjuvant therapy for this disease. hydroalcoholic extract of thymus daenensis has various components such as flavonoids which contribute to gastroprotection. experimental: 35 sprague dawley rat...

In the present study, we investigate the antiulcerogenic effect of gallic acid against aspirin plus pyrolus ligation-induced gastric ulcer in rats. Rats were treated with gallic acid (100 and 200 mg/kg) and famotidine (20 mg/kg) for 1 week, followed by induction of gastric ulcer using the aspirin plus pyrolus ligation model. At the end of 4 h after ligation, the rats were sacrificed and ulcer i...