We describe a case of acute liver failure and death associated with the use of a preparation containing the "natural" anxiolytic kava (Piper methysticum) and passionflower (Passiflora incarnata). The patient died after a report by the Therapeutic Goods Administration (TGA) warning of the potential for hepatotoxicity associated with the use of kava-containing products. The general public and alt...

The sequestrate Rhodactina was originally proposed as a monotypic genus to accommodate R. himalayensis and was suggested be a member of the Gautieriaceae because of similarities in spore ornamentation. Our results, based on atp6 sequences, however, place Rhodactina in the Boletaceae. In addition to the type species, a new species, R. incarnata, from northern Thailand is described and illustrate...

Twenty-nine new oxypregnane glycosides were obtained along with two known cardenolides, frugoside and gofruside, and three known 12-O-acylated pregnane glycosides from the roots of Asclepias incarnata L. (Asclepiadaceae). By detailed studies of the 1H- and 13C-NMR spectra, the structures were determined to be tri- to penta glycosides of isolineolon, 12-O-acetyllineolon, ikemagenin, 12-O-benzoyl...

A critical study of the herbarium material representing orchid genus Dactylorhiza Necker ex Nevski in Kazakhstan was conducted 2019–2020. The information on species composition clarified. fuchsii subsp. hebridensis (Wilmott) Soó and D. × kerneri (Soó) were identified for first time country. New taxa noted individual botanical geographical areas. All presented list annotated with studied materia...

Depression is the most common illness observed in the elderly, adults, and children. Antidepressants prescribed are usually synthetic drugs and these can sometimes cause a wide range of unpleasant side effects. Current research is focussed on natural products from plants as they are a rich source of potent new drug leads. Besides Hypericum perforatum (St. John's wort), the plants studied includ...

Potential mechanisms of Passiflora incarnata extracts and the effect of extraction methods on ingredients and biological effects were explored. Using the same batch of plant material, total flavonoid yields as measured by high-performance liquid chromatography coupled to diode array detection (HPLC-DAD) increased substantially with hot versus cold extraction methods. Whole Passiflora extract in...

A ansiedade é uma emoção comum e normal, sendo um sinal de alerta que faz parte da vida qualquer ser humano. Porém, quando intensa durável, influenciando negativamente no cotidiano na qualidade do indivíduo, caracteriza-se como patológica. Os medicamentos alopáticos prescritos para tratar mostram ocasionar mais reações adversas comparada aos produtos terapêuticos origem vegetal. Passiflora inca...

Colonization is crucial to habitat restoration projects that rely on the spontaneous regeneration of the original vegetation. However, as a previously declining plant species spreads again, the likelihood of founder effects increases through recurrent population founding and associated serial bottlenecks. We related Amplified Fragment Length Polymorphism markers genetic variation and fitness to...