نتایج جستجو برای: tumor suppressors
تعداد نتایج: 430979 فیلتر نتایج به سال:
It is now evident that the cell cycle machinery has a variety of elements negatively regulating cell cycle progression. However, among these negative regulators in cell cycle control, only 4 have been shown to be consistently involved in the development of human cancers as tumor suppressors: Rb (Retinoblastoma susceptibility protein), p53, and two recently identified cyclin-dependent kinase inh...
The aim of the study colon cancer is to introduce basic information cell and cancer. research on gave about hallmarks cell. exaggerated continuous proliferation, resistance death as well tumor suppressors, angiogenesis, spreading metastasis replicative immortality, symptoms cancer: Frequent bowel dysfunction (Diarrhea-constipation), Abdominal pain, nausea & vomiting, Pain during defecation,...
microRNAs (miRNAs) are a new class of non-protein-coding, endogenous, small RNAs. They are important regulatory molecules in animals and plants. miRNA regulates gene expression by translational repression, mRNA cleavage, and mRNA decay initiated by miRNA-guided rapid deadenylation. Recent studies show that some miRNAs regulate cell proliferation and apoptosis processes that are important in can...
Angiomotin (Amot) family contains three members: Amot (p80 and p130 isoforms), Amot-like protein 1 (Amotl1), and Amot-like protein 2 (Amotl2). Amot proteins play an important role in tube formation and migration of endothelial cells and the regulation of tight junctions, polarity, and epithelial-mesenchymal transition in epithelial cells. Moreover, these proteins regulate the proliferation and ...
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