Background: Gastric and colorectal adenocarcinoma are the second and the fifth most common cancers in Iran, respectively. Expression of cytokeratin 7 (CK7) is established in most malignancies including gastric and colorectal adenocarcinoma. Demonstration of Ck7 could be related to prognostic factors and help to the better management of the patients. The objective of our study was to evalu...

conclusions expression of hmgb1 and c-iap2 proteins was associated with hcc development and progression, and the expression of hmgb1 and c-iap2 proteins in hcc were significantly associated with each other. additionally, these proteins may show promise as biomarkers to predict hcc progression. background hepatocellular carcinoma (hcc) is one of the most important health problems in china. objec...

This paper investigates the e ect of family size and birth order on educational attainment. An instrumental variables approach is used to identify the e ect of family size. Instruments for the number of children are twins at last birth and the sex mix of the rst two children. The e ect of birth order is identi ed, by examining the relation with years of education for di erent family sizes separ...

Researchers from around the world met for two days in April this year in Rome, Italy, to discuss progress in the rapidly developing field of Hippo signaling, which is relevant to cancer and the control of organ size. Most of the participants presented data related to previously uncharacterized proteins that physically and functionally interact with known components of the Hippo pathway and regu...

objective: n-nitroso-n-methylurea (nmu) induces breast cancer in rodents, particularly in rats. this model of breast cancer is very similar to human breast cancer. as a continuation of our recent work, we investigated the expressions of cyclin d1 and p21 in nmu-induced breast cancer of wistar albino rats. materials and methods: in this experimental study, mammary carcinoma was induced in female...

background pancreatic neuroendocrine tumors (pnets) are rare tumors with variable malignant potential, prognosis, and survival. we aimed to assess the characteristics of patients with non- functional pnet  in our hospital . methods from nov 2010 to nov 2013 , all patients who came to endosonography unit of shariati  hospital , tehran , iran , and   had pancreatic lesions were assessed . tumor s...

Tumor size seems to be a determinant in the prognosis of early cervical cancer. Patients with tumor size greater than 4 cm (bulky) in diameter have worse outcome.' The purpose of this study was to compare the efficacy of preoperative combined chemoradiation and neoadjuvant chemotherapy (NArC) programs followed by radical hysterectomy in stage Ib - lIb bulky cervical cancer. From September ...