tumor necrosis factor alpha

The aim of the present study was to determine the level of Tumor necrosis factor-alpha in aqueous humor and serum of patients with pseudo exfoliation syndrome. The materials and methods in this study, we measured the level of Tumor necrosis factor-alpha, in aqueous and serum of patients with pseudo exfoliation syndrome and compared the findings with healthy controls. The Results are Regarding A...

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Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific.

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1991

M Lewis L A Tartaglia A Lee G L Bennett G C Rice G H Wong E Y Chen D V Goeddel

Complementary DNA clones encoding two distinct tumor necrosis factor receptors were isolated from a mouse macrophage cDNA library. The cDNA for murine tumor necrosis factor receptor type 1 (mTNF-R1) predicts a mature polypeptide of 425 amino acids that is 64% identical to its human counterpart, whereas the cDNA of murine tumor necrosis factor receptor type 2 (mTNF-R2) predicts a mature protein ...

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Role of tumor necrosis factor-alpha in myocardial dysfunction and apoptosis during hindlimb ischemia and reperfusion.

Journal: :Critical care medicine 2006

Xiangru Lu Joel A Hamilton Ji Shen Theresa Pang Douglas L Jones Richard F Potter J Malcolm O Arnold Qingping Feng

OBJECTIVE Peripheral vascular surgery involving limb ischemia/reperfusion is associated with tumor necrosis factor-alpha production and an increased risk of cardiac complications. The objective of this study was to investigate the role of tumor necrosis factor-alpha in myocardial apoptosis and dysfunction following hindlimb ischemia/reperfusion. DESIGN Randomized perspective animal study. S...

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