نتایج جستجو برای: tumor necrosis factor α tnf α
تعداد نتایج: 1355101 فیلتر نتایج به سال:
به نظر می رسد که فاکتور های ژنتیکی مستعد کننده به بیماری بهجت در پیشرفت بیماری نقش مهمی دارند. سطح سرمی فاکتور نکروز کننده¬ی توموری (tnf) در بیماران مبتلا به بهجت بالا می¬رود و پاسخ مثبت افراد بیمار به درمان آنتی بادی tnf-α نشان دهنده¬ی نقش tnf در بیماری بهجت است. در این مطالعه توزیع دو تا از پلی¬مورفیسم¬های ناحیه¬ی پروموتوری ژن tnf-α (tnf-α -1031t/c & tnf-α -308g/a) در 53 فرد بیمار و 79 فرد ک...
background : most diagnostic tests for biliary atresia (ba) are invasive. this study evaluates the sensitivity and specificity of serum tumor necrosis factor-α (tnf-α) for diagnosing extra hepatic biliary duct atresia (ehba) in infants. materials and methods : infants with cholestasis who were admitted to children′s medical center hospital were evaluated. a total of 50 infants (20 with ehba an...
Tumor necrosis factor-α (TNF-α), an important factor in systematic inflammation, is reportedly involved in several cancer types. The TNF-α -308 G>A (rs1800629) polymorphism in the promoter region influences TNF-α production. The association between TNF-α -308 G>A polymorphism and colorectal cancer (CRC) is not fully understood, especially the connections between TNF-α -308 G>A polymorphism and ...
Background: Studies have been carried out to evaluate the association of tumor necrosis factor-α (TNF-α) gene promoter region polymorphisms with recurrent pregnancy loss (RPL) risk. However, the results remain controversial and incomplete. Hence, we performed a meta-analysis to evaluate the association of TNF-α -308G>A and -238G>A polymorphisms with RPL risk. Materials and Methods: A comprehens...
Background: Tumor Necrosis Factor Alpha (TNF-α) gene, as an inflammatory factor, plays an important role in reproductive physiology, especially in women with Polycystic Ovary Syndrome (PCOS). Objective: This study aims to investigate the relationship between the -1031 T/C polymorphism of TNF-α gene and biochemical factors in women with PCOS. Methods: In this case-control study, participants w...
We present a label-free biosensor based on electrochemical impedance spectroscopy for the detection of proinflammatory cytokine Tumor Necrosis Factor (TNF-α). Secretion of TNF-α has been correlated to the onset of various diseases including rheumatoid arthritis, Crohn’s disease etc. Gold electrodes were patterned on a silicon substrate and self assembled monolayer of dithiobis-succinimidyl prop...
rheumatoid arthritis is the most common inflammatory joint disease with 1 percent prevalence in community which presents with symmetrical polyarthritis of hands with inflammatory behavior. several studies in recent years were conducted for evaluation of inflammatory cytokines such as il1-α (interlukin 1α) and tnf- α (tumor necrosis factor) in rheumatologic disorders including rheumatoid arthrit...
Elevated serum concentrations of leucine-rich α-2-glycoprotein (LRG1) have been reported in patients with inflammatory, autoimmune, and cardiovascular diseases. This study aims to investigate the role LRG1 endothelial activation. cells (ECs) arteries critical limb ischemia (CLI) was assessed by immunohistochemistry ELISA, respectively. expression sheared tumor necrosis factor-α (TNF-α)-treated ...
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