The syndrome produced by lesion of the septum in animals can serve as a functional research model of human disinhibitory psychopathology. Disinhibitory psychopathology appears to span several traditionally separate psychological categories—psychopathy, hysteria, hyperactivity, antisocial and impulsive personality, and alcoholism. It is proposed that these categories are separate manifestations ...

Platelet function disorder in the presence of normal platelet count has been reported to lead variable clinical phenotypes [1]. Differential diagnosis these bleeding diathesis types much more complex than thrombocytopenic conditions.

A stress-diathesis explanatory model of suicidal behaviour has proved to be of heuristic value, and both clinical and neurobiological components can be integrated into such a model. A trait deficiency in serotonin input to the anterior cingulate and ventromedial prefrontal cortex is found in association with suicide, and more recently non-fatal suicidal behaviour, and is linked to decision-maki...

Accurate prediction of suicide risk remains a challenge, in its prevention. Many people with psychiatric disorders do not manifest suicidal behaviour, suggesting the importance of diathesis, or susceptibility to suicide, in addition to associated disorders. At present there are no biomarkers to predict suicidal behaviour. The authors of this article have attempted to describe the neurobiology o...

In this paper we examine the relationships among diathesis alternations, the semantics of verbs, and the referential status of NPs. Some diathesis shifts are argued to involve changes in the semantic type of NP arguments, including possible alternations between ‘referential’ NPs and ‘property-type’ NPs. We explore applications of this approach to alternations of Genitive and Accusative, both wi...