It is well known that after Bacille Calmette-Gue'rin (B.C.G.) vaccination the degree of allergy as shown by the tuberculin test is of a lesser order than that after infection with virulent tubercle bacilli. For this reason it may be necessary to perform several successively stronger tuberculin tests up to 100 units of old tuberculin (Mantoux 1/100) before a positive post-vaccination test is obt...

In the present study, T-Spot.TB and the tuberculin skin test (TST) were compared in the screening of latent tuberculosis infection among silicotic patients. A conditional probability model was used to compare the potential clinical utilities of T-Spot.TB and TST performed on 134 silicotic subjects from December 1, 2004 to January 31, 2007. Data from a historical cohort were also reanalysed for ...

background: the risk of developing tuberculosis is high among chronic hemodialysis patients. the tuberculin skin test (tst) has been in use for diagnosing latent tb, but few data are available on tst in hemodialysis patients. objective: this study was done to identify the tst reactivity and frequency of booster effect in serial tst among hemodialysis patients. methods: a total of 100 patients i...

recent studies have proposed that a decline in bacterial infections such as tuberculosis is a factor underlying the rising prevalence and severity of atopic disorder in developed countries. there are conflicting ideas about the inverse relationship between bcg (bacillus calmette-guerin) vaccination and asthma. stronger response to tuberculin test as an indicator of more potent th1 response is s...

IN 1890 Professor Koch, who had discovered the tubercle bacillus in 1882, announced that he had discovered a remedy for tuberculosis in tuberculin, made by growing virulent tubercle bacilli in a 5 per cent. glycerol broth medium for six to eight weeks at 38°C., the mature culture being sterilised in a water bath at 100GC., evaporatedl to one-tenth of its original volume, and filtered. The filtr...

conclusion skin test anergy is uncommon among drug users and the ppd skin test may be reliably used for the identification of latent tb infection in the population. results a total of 221 patients (216 male, mean age 43.5 ± 14.3 years) were studied. tuberculin skin test results showed that 87 subjects (39.4%) tested positive for tb reactivity. reactivity to tetanus and candida antigens were obs...

assistance of Ms. Marlette Brown. REI tIur.r. CEs 1 American Academy of Pediatrics, Section on Diseases of the Chest: The tuberculin test. Pediatrics 54:650-652, 1974 2 Edwards PQ: Tuberculin testing of children. Pediatrics 54: 628-630, 1974 3 Maqbool S, Asnes RS, Grebin B: Tine test compliance in a clinic setting. Pediatrics 55:388-391, 1975 4 Weinberger HK, Terry C: Tuberculin testing in a pe...

One hundred and two patients with inoperable bronchial carcinoma who had tuberculin tests at the time of diagnosis were followed up to see if there was any correlation between their degree of tuberculin reactivity and their subsequent survival time. There was a significant difference in survival between positive and negative tuberculin reactors (Log Rank Test P less than 0.05), the former havin...

The tuberculin for Mantoux-test is neither heated nor filtered after diluting, of course. Heating of a diluted tuberculin was once made half in fun. And as stated in section 3.1 and 6.1, a diluted tuberculin was sealed in ampuls, and heated by autoclaving for 20 minutes at 15 pounds pressure (120•Ž). After this precedure we saw a curious result: the potency was lost on the whole, of course, but...

Tuberculin purified protein derivative (PPD) has been prepared by seven different precipitation methods from culture filtrate of Mycobacterium tuberculosis var. hominis. It was found to contain 48 to 99% tuberculoprotein, depending on the method of precipitation. The remaining percentage is represented by nucleic acid, polysaccharide, and ash. Activation analysis on tuberculin PPD and on tuberc...