Treatment failures in head and neck cancer patients are mainly related to locoregional tumor recurrence. The objective of the present study was to evaluate the diagnostic accuracy of model-free dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to detect local recurrence during the surveillance of head and neck cancer patients.Our retrospective study enrolled 24 patients with primar...

We present a novel method for computing the information content of an image. We introduce the notion of task-specific information (TSI) in order to quantify imaging system performance for a given task. This new approach employs a recently-discovered relationship between the Shannon mutual-information and minimum estimation error. We demonstrate the utility of the TSI formulation by applying it ...

the present study aimed to investigate the characteristics of occupational accidents and frequency and severity of work related accidents in the construction industry among iranian insured workers during the years 20072011.the iranian social security organization (isso) accident database containing 21,864 cases between the years 2007-2011 was applied in this study. in the next step, total accid...

Interdisciplinary design methods used in the development of the Constructed Narratives project, which is a tangible social interface (TSI). The TSI is designed to enable users to collaboratively construct and negotiate their social and knowledge networks based upon their preferences and user profiles. [13]

PURPOSE Trachoma is a fibrotic disease of the conjunctiva initiated by Chlamydia trachomatis infection. This blinding disease affects over 40 million people worldwide yet the mechanisms underlying its pathogenesis remain poorly understood. We have investigated host microRNA (miR) expression in health (N) and disease (conjunctival scarring with (TSI) and without (TS) inflammation) to determine i...

BACKGROUND AND PURPOSE Brains of patients with multiple sclerosis (MS) characteristically have "black holes" (BHs), hypointense lesions on T1-weighted (T1W) spin-echo (SE) images. Although conventional MR imaging can disclose chronic BHs (CBHs), it cannot stage the degree of their pathologic condition. Tissue-specific imaging (TSI), a recently introduced MR imaging technique, allows selective v...

From a mechanistic viewpoint, it is desirable to predict the distribution of species based on ecological parameters (e.g. rainfall or temperature) that are causal factors for their distribution. Data for such ecological factors are difficult or expensive to collect and are usually insufficient. Terrain-related variables are used as proxies of ecological factors in the study since data for them ...

[1] Variations in the total solar irradiance (TSI) associated with solar activity have been argued to influence the Earth’s climate system, in particular when solar activity deviates from the average for a substantial period. One such example is the 17th Century Maunder Minimum during which sunspot numbers were extremely low, as Earth experienced the Little Ice Age. Estimation of the TSI during...

We present a human miRNA tissue atlas by determining the abundance of 1997 miRNAs in 61 tissue biopsies of different organs from two individuals collected post-mortem. One thousand three hundred sixty-four miRNAs were discovered in at least one tissue, 143 were present in each tissue. To define the distribution of miRNAs, we utilized a tissue specificity index (TSI). The majority of miRNAs (82....

Hashimoto’s patients have in some cases both stimulating and blocking antibodies [2, 3]. It stands to reason that if the patient is hypothyroid, then blocking antibody avidity and/ or titer would dominate irrespective of the presence of stimulating antibodies. There is a growing list of publications that show the prevalence of TSHR stimulating autoantibodies in HT patients using bioassays. Wall...