AhpF, the alkyl hydroperoxide reductase component which transfers electrons from pyridine nucleotides to the peroxidase protein, AhpC, possesses two redox-active disulfide centers in addition to one FAD per subunit; the primary goal of these studies has been to test for the requirement of one or both of these disulfide centers in catalysis. Two half-cystine residues of one center (Cys345Cys348)...

Ground granulated blast furnace slags (GGBS) are glassy by-products from iron production that commonly used as supplementary cementitious materials in blended cements. The glass structure of seven industrial GGBS was investigated by Raman and nuclear magnetic resonance spectroscopies. complex composition the induced multiple analytical challenges. Under usual continuous excitation, signal maske...

BACKGROUND Clinical data gathered for administrative purposes often lack sufficient information to separate the records of radiotherapy given for palliation from those given for cure. An absence, incompleteness, or inaccuracy of such information could hinder or bias the study of the utilization and outcome of radiotherapy. This study has three specific purposes: 1) develop a method to determine...

The sodium channel blocker mexiletine is considered the first-line drug in myotonic syndromes, a group of muscle disorders characterized by membrane over-excitability. We previously showed that the β-adrenoceptor modulators, clenbuterol and propranolol, block voltage-gated sodium channels in a manner reminiscent to mexiletine, whereas salbutamol and nadolol do not. We now developed a pharmacolo...

The main aim of this work is to investigate the actuator driving force variations of a parallel kinematic machine (PKM) for different cutting paths. To meet this aim, a TRR-XY Ž ve-degrees-of-freedom (5DOF) PKM was selected and built for this research, and a dynamic analysis model of the PKM was developed. Here, ‘T’ stands for translational DOF and ‘R’ stands for rotational DOF of the platform....

Citation: Al Disi ZA, Jaoua S, Bontognali TRR, Attia ESM, Al-Kuwari HAAS and Zouari N (2017) Evidence of a Role for Aerobic Bacteria in High Magnesium Carbonate Formation in the Evaporitic Environment of Dohat Faishakh Sabkha in Qatar. Front. Environ. Sci. 5:1. doi: 10.3389/fenvs.2017.00001 Evidence of a Role for Aerobic Bacteria in High Magnesium Carbonate Formation in the Evaporitic Environme...

INTRODUCTION Nuclear receptors (NRs) function as transcription factors that respond to cellular signals to initiate new gene expression programs (King-Jones and Thummel, 2005) and have essential roles in embryonic development, growth and differentiation. NRs collaborate with co-factors (>300) that provide important enzymatic and regulatory functions (Lonard and O’Malley, 2007; Lonard and O’Mall...

Beilchmiedia miersii (Gay) Kosterm (Belloto of the North), an endemic species central Chile, belongs to hydrophilous forest subtype within sclerophyllous ecosystem; it is azonal in character and fragmented distribution. Preferably, its populations are found near stream areas, given high water needs, a situation that aggravated by intense prolonged drought affects area where grows. B. faces stro...

BACKGROUND The secreted protein acidic and rich in cysteine (SPARC) plays a pivotal role in regulating cell-matrix interactions and tumor angiogenesis, proliferation, and migration. Detection of SPARC gene methylation may be useful as a tumorigenesis marker for early detection of pancreatic cancer. METHODS Methylation of the SPARC gene transcriptional regulation region (TRR) was detected usin...