Pancreatic carcinoma ranks among the most lethal of human cancers. Besides late detection, other factors contribute to its lethality, including a high degree of chemoresistance, invasion, and distant metastases. Currently, the mainstay of therapy involves resection of local disease in a minority of patients (Whipple procedure) and systemic gemcitabine. While systemic chemotherapy has some benef...

OBJECTIVE The potential of NaHCO3 versus human serum to induce germ tube formation in Candida albicans was investigated. SPECIMENS A total of 100 isolates were obtained from oral swabs of patients presenting with thrush. Approval for the study was granted by the Joint Research Ethics Committee (JREC/23/08). METHOD Confirmed C. albicans isolates by routine methods were tested for germ tube i...

This study aims to investigate whether different player-matching mechanisms in educational multi-player online games (MOGs) can affect students’ learning performance, enjoyment perception and gaming behaviors. Based on the multi-player quiz game, TRIS-Q, developed by Tsai, Tsai and Lin (2015) using a free player-matching (FPM) mechanism, the same game, but incorporating an automatic player-matc...

The C3-symmetric chiral propylated host-type ligands (±)-tris(isonicotinoyl)-tris(propyl)-cyclotricatechylene (L1) and (±)-tris(4-pyridyl-4-benzoxy)-tris(propyl)-cyclotricatechylene (L2) self-assemble with Pd(II) into [Pd6L8](12+) metallo-cages that resemble a stella octangula. The self-assembly of the [Pd6(L1)8](12+) cage is solvent-dependent; broad NMR resonances and a disordered crystal stru...

A series of molybdenum(VI) complexes containing bidentate ligands: toluene-3,4-dithiol (1), 2-mercaptophenol (2), 2-aminothiophenol (3), ethane-1,2-dithiol (4), dithiooxamide (5) and 2-thiopheno-carboxamide (6) are reported. The hexacoordinated molybdenum tris-chelates compounds: tris-(toluene-3, 4-dithiolate)molybdenum(VI) (7), tris-(2-mercaptophenolate)molybdenum(VI) (8), tris-(2-aminothiophe...

The coordination versatility of a 1,3,5-triphenylbenzene-tris-mesoionic carbene ligand is illustrated by the preparation of complexes with three different metals: rhodium, iridium and nickel. The rhodium and iridium complexes contained the [MCl(COD)] fragments, while the nickel compound contained [NiCpCl]. The preparation of the tris-MIC (MIC = mesoionic carbene) complex with three [IrCl(CO)2] ...

Tris(hydroxymethyl)aminomethane (Tris) has been used as the buffer in bioactivity testing for over two decades and become a standard choice scientific community. While it is believed to be non-interacting, extent of its interactions with titanium oxide surfaces not systematically studied. Here, we use experimental (zeta potential measurements) computational (molecular dynamics) approaches evalu...