We recently showed that defined sets of transcription factors are sufficient to convert mouse and human fibroblasts directly into cells resembling functional neurons, referred to as "induced neuronal" (iN) cells. For some applications however, it would be desirable to convert fibroblasts into proliferative neural precursor cells (NPCs) instead of neurons. We hypothesized that NPC-like cells may...

BACKGROUND CD133 (Prominin) is widely used as a marker for the identification and isolation of neural precursor cells from normal brain or tumor tissue. However, the assumption that CD133 is expressed constitutively in neural precursor cells has not been examined. METHODOLOGY/PRINCIPAL FINDINGS In this study, we demonstrate that CD133 and a second marker CD15 are expressed heterogeneously in ...

analysis of time series data can involve the inversion of large covariance matrices. for theclass of arma (p, q) processes there are no exact explicit expressions for these inverses, except for thema (1) process. in practice, the sample covariance matrix can be very large and inversion can becomputationally time consuming and so approximate explicit expressions for the inverse are desirable.thi...

‎the global fom and gmres algorithms are among the effective‎ ‎methods to solve sylvester matrix equations‎. ‎in this paper‎, ‎we‎ ‎study these algorithms in the case that the coefficient matrices‎ ‎are real symmetric (real symmetric positive definite) and extract‎ ‎two cg-type algorithms for solving generalized sylvester matrix‎ ‎equations‎. ‎the proposed methods are iterative projection metho...

let and be a sequence with non-negative entries. if , denote by the infimum of those satisfying the following inequality: whenever . the purpose of this paper is to give an upper bound for the norm of operator t on weighted sequence spaces d(w,p) and lp(w) and also e(w,?). we considered this problem for certain matrix operators such as norlund, weighted mean, ceasaro and copson matrices. th...