An aircraft is said to be operated in a trim condition when the body axis accelerations are zero. In other words, no resultant forces or torque act on the aircraft. The purpose of the longitudinal controller of an aircraft is to help pilots to move the aircraft from one trim condition to another, or to stabilize the aircraft in an operating trim condition while the aircraft is subjected to dist...

1. Introduction Two primary prerequisites for a safe flight are stability and controllability. In addition, pilot and occupant's comfort is of significant importance which is often referred to as handling qualities. These three aircraft design objectives will influence the design of control surfaces and create variety of design constraints. Flight stability is defined as the inherent tendency o...

BACKGROUND Military personnel exposed to potentially traumatic events whilst deployed on operational duties may develop psychological problems. The Royal Marines have made extensive use of Trauma Risk Management (TRiM), a peer-support system that operates through practitioners embedded within operational units. TRiM aims to promote recognition of psychological illness and to facilitate social s...

In this work, we present a global potential energy surface for the ground electronic state of the H4(+) based on ab initio calculations. The final fit is based on triatomics-in-molecules (TRIM) approximation and it includes extra four-body terms for the better description of some discrepancies found on the TRIM model. The TRIM method itself allows a very accurate description of the asymptotic r...

Recurrent viral pressure has acted on host-encoded antiviral genes during primate and mammalian evolution. This selective pressure has resulted in dramatic episodes of adaptation in host antiviral genes, often detected via positive selection. These evolutionary signatures of adaptation have the potential to highlight previously unrecognized antiviral genes (also called restriction factors). Alt...

The innate antiviral response is integral in protecting the host against virus infection. Many proteins regulate these signaling pathways including ubiquitin enzymes. The ubiquitin-activating (E1), -conjugating (E2), and -ligating (E3) enzymes work together to link ubiquitin, a small protein, onto other ubiquitin molecules or target proteins to mediate various effector functions. The tripartite...

The members of tripartite-motif containing (TRIM) protein participate in various cellular processes and play an important role in host antiviral function. TRIM proteins exert their antiviral activity either directly by degrading viral proteins through their E3 ligase activity, or indirectly by promoting host innate immunity. This study demonstrated for the first time that TRIM52 is a novel anti...

It is well established that inlet flow characteristics may affect the performance of fluid handling systems considerably. This work focuses on the local flow analysis of a severe service control valve with a continuous resistance trim (CRT) operating under multiphase flow conditions and the effect of the inlet flow characteristics on the dispersed phase distribution within the trim and the valv...

Objectives. Normal and neoplastic human tissues have different electromagnetic properties. This study aimed to determine the diagnostic accuracy of noninvasive electromagnetic detection of bladder cancer (BC) by the tissue-resonance interaction method (TRIM-prob). Patients and Methods. Consecutive patients were referred for cystoscopy because of (i) microscopic or gross hematuria and/or irritat...