Background Sexually transmitted infections (STIs) are one of the major causes of acute illness, infertility, long term disability and death for millions of men, women and infants globally. Trichomonas vaginalis, Neisseria gonorrhea and Chlamydia trachomatis are well established agents of STIs leading to vaginal discharge in women. However, the prevalence and co infection patterns among symptoma...

Ro 7-0207 is a light yellow, crystalline substance with a melting range of 74-79oC. The pH of a 1 per cent. aqueous solution is about 6-6. In water its solubility is 2-4 per cent. at 25°C. In 95 per cent. ethanol its solubility is > 50 per cent. at 25GC. Aqueous solutions (0-5 per cent.) are relatively stable upon heating at 100GC. for 1 hr. except at pH values above 7. Ro 7-0207 is an effectiv...

OBJECTIVE The objectives of this study were to 1) determine the prevalance and characterize the symptomatology of Trichomonas vaginalis (TV) infection in pregnant women on entry into prenatal care in an inner-city population; 2) compare conventional microscopic methods vs. culture techniques in diagnosing TV in both symptomatic and asymptomatic pregnant patients; and 3) correlate wet mount micr...

Seventy-three men with urogenital trichomonal infection were treated with a single daily dose of 1 g tinidazole or 1.5 g metronidazole. Both treatments gave satisfactory results. Wives who were also infected with Trichomonas vaginalis, were less likely to have a recurrence of the infection after their husbands had been given either drug.

Trichomonas vaginalis (TV) infection is the most prevalent curable sexually transmitted infection in the United States and worldwide. Most TV infections are asymptomatic, and the accurate diagnosis of this infection has been limited by lack of sufficiently sensitive and specific diagnostic tests, particularly for men. To provide updates for the 2010 Centers for Disease Control and Prevention's ...

Management of a 42 year old female patient diagnosed with trichomoniasis is described. She failed to respond to recommended oral and high dose oral and topical metronidazole. Various options used in previously reported cases of metronidazole resistant trichomoniasis also failed to cure her condition. MIC showed the organism to be resistant to metronidazole. Cure was achieved with the use of top...

A rapid and specific dot-enzyme immunoassay (DIBA) using monoclonal antibody was introduced for detection of Trichomonas vaginalis antigen in vaginal and urethral materials. The results of DIBA were compared with culture findings of the parasite in 245 female patients. Taking culture as the reference method, DIBA had a sensitivity of 92% and a specificity of 93%. The predictive value of a posit...

Although many investigations into Trichomonas vaginalis Donne 1875 and vaginal trichomoniasis have been made since the organism was recognized again as a pathological entity by Hohne in 1916, problems on its pathogenicity, epidemiology and therapeutics are still left in confusion. One of the main reasons of this confusion appears that the bacteria free cultivation of this organism has not been ...

Trichomonas vaginalis was first described by Donne (1836), who observed the organism in purulent secretions in both women and men, and stated that it was not present in normal vaginal secretions. T. vaginalis was successfully cultured in vitro by Lynch (1915), and there have since been a number of publications containing descriptions of the morphological, epidemiological, and pathological aspec...