نتایج جستجو برای: tricarboxylic acid cycle
تعداد نتایج: 999374 فیلتر نتایج به سال:
Following traumatic brain injury, complex cerebral energy perturbations occur. Correlating with unfavourable outcome, high brain extracellular lactate/pyruvate ratio suggests hypoxic metabolism and/or mitochondrial dysfunction. We investigated whether focal administration of succinate, a tricarboxylic acid cycle intermediate interacting directly with the mitochondrial electron transport chain, ...
It is not yet possible to interpret thesc results completely. The acids affected are all dicarboxylic acids with a chain length of between C, and Cs. The glutarate derivatives showed the greatest increases. Citrate excretion was unchanged (Bond et d., 1972). This suggests that the range of compounds affected is determined by chemical structure rather than metabolic relationship, and that this i...
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