نتایج جستجو برای: triazole derivative
تعداد نتایج: 68824 فیلتر نتایج به سال:
β-Methoxyacrylate group is an important pharmacophore of commercially used strobilurin fungicides. In the present study, a total of seventeen 1,2,4-triazole thiols 8a-h and 1,2,3-triazole substituted 10a-i strobilurin derivatives have been synthesized. 1,2,4-Triazole thiol substituted strobilurin derivatives 8a-h have been found to inhibit the growth of plant pathogens such as Fusarium oxysporu...
Apoptosis or programmed cell death is critical for embryogenesis and tissue homeostasis. Uncontrolled apoptosis leads to different human disorders including immunodeficiency, autoimmune disorder and cancer. Several small molecules that control apoptosis have been identified. Here, we have shown the functional role of triazole derivative (DCPTN-PT) that acts as a potent HDAC inhibitor and mis-ex...
Introduction: Omeprazole is one of the most used proton-blocking molecules applied in gastric ulcer treatment. Its blocking effect achieved by presence both acidic and basic nitrogen heteroatoms its composition. Nevertheless, due to collateral effects, which may be moderate severe, development electrochemical determination really actual. Methods: In this work, we describe theoretically possibil...
The present work includes synthesis of new series heterocyclic derivatives containing 6-amino-1,3-dimethyl uracil moiety linked to 1,2,4-triazole [6-8 and 10]. first way reaction 6-amino-1,3-dimethyluracil with ethyl chloroacetate K2CO3 as catalyst in DMF solvent gives ester derivative [1]. Then, compound [1] was converted into (semicarbazide, thiosemicarbazide, phenylsemicarbazide hydrazide de...
The Front Cover illustrates the simplicity and selectivity of modification organic donor–acceptor photocatalysts by click chemistry. connection an alkyne bearing 4CzIPN derivative with azide forming a triazole-linker to tune catalyst's photoelectronic properties is just as simple putting together puzzle pieces. In background luminescent yellow solution new photoredox catalyst irradiated blue li...
Abstract: 5,5 ′ -Methylenebis(4–phenyl-4H -1,2,4-triazole-3-thiol) (2) was synthesized starting from hydrazinecarbothioamide compound (1). Treatment of compound 2 with ethyl bromoacetate produced diethyl 5,5 ′ -{methylenebis[(4phenyl-4H -1,2,4-triazole-5,3-diyl)thio]}diacetate (3), which was converted to the corresponding diacetohydrazide derivative (4) by treatment with hydrazine hydrate. The ...
In this work, we describe theoretically the possibility of omeprazole electrochemical determination, assisted by composite containing vanadium oxyhydroxide as an active substance and polymer 1,2,4-triazolic derivative a mediator. The molecule undergoes sulfoxide to sulfide reduction process over trivalent compound. oxyhydroxide, at its turn, may be oxidized tetravalent state, represented in two...
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