BACKGROUND Estimates of the effectiveness of neurofeedback as a treatment for attention-deficit hyperactivity disorder (ADHD) are mixed. AIMS To investigate the long-term additional effects of neurofeedback (NFB) compared with treatment as usual (TAU) for adolescents with ADHD. METHOD Using a multicentre parallel-randomised controlled trial design, 60 adolescents with a DSM-IV-TR diagnosis ...

Using treatment as usual (TAU) in trials has obscured the repeated finding that assertive outreach has never reduced hospitalisation when compared with treatment by multidisciplinary teams (community mental health teams, CMHTs). Its use has delayed recognising that CMHTs are the more cost-effective, evidence-based approach. The term should be abandoned and trials should compare two equally well...

OBJECTIVE Mindfulness-based cognitive therapy (MBCT) has recently been proposed as a treatment option for chronic depression. The cognitive behavioral analysis system of psychotherapy (CBASP) is the only approach specifically developed to date for the treatment of chronically depressed patients. The efficacy of MBCT plus treatment-as-usual (TAU), and CBASP (group version) plus TAU, was compared...

BACKGROUND Major depression is a common psychiatric disorder, frequently taking a chronic course. Despite provision of evidence-based treatments, including antidepressant medication and psychological treatments like cognitive behavioral therapy or interpersonal therapy, a substantial amount of patients do not recover. Mindfulness-Based Cognitive Therapy (MBCT) has been found to be effective in ...

Encopresis is a significant medical problem for millions of children. Despite its prevalence, poor treatment success rates indicate that it is often difficult to treat. The goal of this study was to evaluate an Internet intervention for encopresis (UCanPoopToo) with children from across the US. A 2 (Group) 3 (Time) RCT was used to evaluate the efficacy of UCanPoopToo. Participants were randomiz...

Abstract Diabetes Mellitus (DM) is the most common metabolic disorder and cause of death in eastern populations, with prevalence estimated to be at level epidemic illness. Despite medical attention, psychological factors remain a significant contributor DM, requiring effective interventions. This study evaluated effects Mindfulness-integrated Cognitive Behavior Therapy (MiCBT) on depression, tr...

This study examined whether acceptance and commitment therapy (ACT) enhances treatment as usual (TAU) in improving treatment outcomes in patients with alcohol use disorder (AUD) and comorbid affective disorder. Fifty-two participants were included in the study, of whom 26 were patients with AUD and either depression or bipolar disorder treated with ACT group therapy in parallel with TAU (inpati...

Abstract: Background The OPUS trial is the largest randomized controlled (RCT) testing early intervention services with 20-years of follow-up among individuals a first episode psychosis in schizophrenia spectrum. Methods A total 547 spectrum were included into I between January 1998 - December 2000 and allocated to either two years or treatment as usual. Clinical trained staff, blinded original...