[Purpose] The purpose of the present study was to examine the effects of progressive body weight supported treadmill forward and backward walking training (PBWSTFBWT), progressive body weight supported treadmill forward walking training (PBWSTFWT), progressive body weight supported treadmill backward walking training (PBWSTBWT), on stroke patients' affected side lower extremity's walking abilit...

nowadays, research on exercise physiology has developed. many of studies try to discover body responses or adaptations to exercise training or physical activity. in many cases, human beings are not suitable models to study these mechanisms in vivo due to ethical and legal limitations. laboratory animals especially mice and rats are appropriate models for these researches. treadmill is an excell...

OBJECTIVE This phase II study investigated the feasibility and potential effectiveness of treadmill training versus normal gait re-education for ambulant and non-ambulant people with sub-acute stroke delivered as part of normal clinical practice. DESIGN A single-blind, feasibility randomized controlled trial. SETTING Four hospital-based stroke units. SUBJECTS Participants within three mon...

Jiawei Shenqi-wan (JSQW), which comprises Shenqi-wan and two additional medicinal herbs, has been widely used for the treatment of various growth impairments, including cerebral palsy. In the present study, JSQW was administered to hypoxic-ischemic Sprague-Dawley rats that underwent treadmill training from 4-7 weeks of age to examine the beneficial effects of combined JSQW and treadmill therapy...

Recent results have shown that exercise training promotes the recovery of injured rat distal spinal cords, but are still unclear about the function of skeletal muscle in this process. Herein, rats with incomplete thoracic (T10) spinal cord injuries (SCI) with a dual spinal lesion model were subjected to four weeks of treadmill training and then were treated with complete spinal transection at T...

QUESTION Does mechanically assisted walking increase walking speed or distance in ambulatory people with stroke compared with no intervention/non-walking intervention, or with overground walking? DESIGN Systematic review with meta-analysis of randomised trials. PARTICIPANTS Ambulatory adults with stroke. INTERVENTION Mechanically assisted walking (treadmill or gait trainer) without body w...

BACKGROUND Parkinson's disease (PD) causes motor and non-motor impairments that affect the subject's quality of life. OBJECTIVE To assess the effects of treadmill-walking training with additional body load on the quality of life and motor function of subjects with PD. METHODS Nine subjects with PD, Hoehn and Yahr stages 2-3, not demented and with capability to ambulate independently took pa...

The aim of this study was to evaluate the effect of early motor balance and coordination training on functional recovery and brain plasticity in an ischemic rat stroke model, compared with simple locomotor exercise. Adult male Sprague-Dawley rats with cortical infarcts were trained under one of four conditions: nontrained control, treadmill training, motor training on the Rota-rod, or both Rota...

Spasticity is an important problem that complicates daily living in many individuals with spinal cord injury (SCI). While previous studies in human and animals revealed significant improvements in locomotor ability with treadmill locomotor training, it is not known to what extent locomotor training influences spasticity. In addition, it would be of considerable practical interest to know how th...

[Purpose] The aim of the present study was to investigate effects of skilled reach training with affected forelimb and treadmill exercise on the expression of neurotrophic factor following ischemia-induced brain injury in rats. [Subjects and Methods] Thirty male Sprague-Dawley rats were divided into 3 groups randomly: namely, the control sacrified 2 weeks after surgery, skilled reach training w...