The challenge of combining these candidates to design an ideal medicine against malaria (Table 5) is formidable. There are still many unknown factors, not the least of which is that only a limited number of new classes of molecules have reached clinical evaluation. It is clear that a single molecule can have more than one attribute: a molecule can for example meet the criteria of more than one ...

Given two points p and q and a finite number of simple polygons in a plane. The basic version of a touring-a-sequence-of-polygons problem (in brief: a touring polygons problem, TPP) is how to find a shortest path such that it starts at p, then it visits these polygons in the given order, and finally it ends at q. This paper describes approximate algorithms for different versions of touring poly...

A 2.75-approximation algorithm is proposed for the unconstrained traveling tournament problem, which is a variant of the traveling tournament problem. For the unconstrained traveling tournament problem, this is the first proposal of an approximation algorithm with a constant approximation ratio. In addition, the proposed algorithm yields a solution that meets both the norepeater and mirrored co...

A sport tournament problem is considered the Traveling Tournament Problem (TTP). One interesting type is the mirrored Traveling Tournament Problem (mTTP). The objective of the problem is to minimize either the total number of traveling or the total distances of traveling or both. This research aims to find an optimized solution of the mirrored Traveling Tournament Problem with minimum total num...

the homogeneous balance method can be used to construct exact traveling wave solutions of nonlinear partial differential equations. in this paper, this method is used to construct newsoliton solutions of the (3+1) jimbo--miwa equation.