Transition metal complexes offer great potential as diagnostic and therapeutic agents, and a growing number of biological applications have been explored. To be effective, these complexes must reach their intended target inside the cell. Here we review the cellular accumulation of metal complexes, including their uptake, localization, and efflux. Metal complexes are taken up inside cells throug...

in this work, we report results of calculations based on the density functional theory of different species metal-ozone, containing mercury, silver and gold. the chosen species range from small molecules and large transition-metal containing ozone with mercury, silver and gold complexes. a comparative analysis of the description of the metal-oxygen bond obtained by different methodologies is pr...

Coordination of the carbocyclic ring of hydroquinones to electrophilic transition-metal fragments such as Mn(CO)3+ and Rh(COD)+ produces stable pi-bonded eta6-complexes that are activated to facile reversible deprotonation of the -OH groups. The deprotonations are accompanied by electron transfer to the transition metal, which acts as an internal oxidizing agent or electron sink. With manganese...

Transition metal-alkane complexes-termed σ-complexes because the alkane donates electron density to the metal from a σ-symmetry carbon-hydrogen (C-H) orbital-are key intermediates in catalytic C-H activation processes, yet these complexes remain tantalizingly elusive to characterization in the solid state by single-crystal x-ray diffraction techniques. Here, we report an approach to the synthes...

a series of transition metal complexes with two thiosemicarbazide schiff bases, 1-(4-dimethylaminobenzyl- idene)thiosemicarbazide (abtsc) and 1-(2-pyridincarboxyl-idene) thiosemicarbazide (tcts) were synthesized with co(ii), ni(ii), zn(ii), cd(ii) and ag(i) salts (chloride and acetate). these complexes were characterized by different methods including proton nuclear magnetic resonance (1hnmr), ...

9. Metal-Responsive MRI Agents 4946 9.1. MRI Agents for Calcium 4946 9.2. MRI Agents for Zinc and Copper 4947 10. Luminescent Metal Complexes for Cellular Imaging 4948 10.1. Luminescent Transition Metal Complexes 4949 10.2. Luminescent Lanthanide Complexes 4950 11. Using Coordination Chemistry To Label Proteins 4951 11.1. Polycysteine Tags 4951 11.2. Polyhistidine Tags 4953 11.3. Polyaspartate ...

The first structurally authenticated [2+2] cycloaddition products of any transition metal hydrazide complexes are reported; cycloaddition products of transition metal hydrazides with alkynes and heteroalkynes have been obtained for the first time; these are the first structurally authenticated cycloaddition products for any transition metal M=NNR(2) functional group.

ligands derived from 8-quinoline, 6-quinoline, 1 -isoquinoline, and 5-isoquinoline were synthesized. these compounds have been used as ligands for complexation of transition metals, such as copper(ii) and nickel(ii). according to the spectrosocopic data, copper(ii) cation forms (i: 1) and (i:2) complexes with 2-(8-quinoly1)-l,l,3,3- tetramethylguanidine and 2- (i '-isoquinoly1)- 1,1,3,3-te...

Development of organometallic chemistry in the past half century is reviewed from the author’s personal viewpoint with focus on the establishment of fundamental concepts relevant to catalysis. Further development in the coming century is expected in view of the diversity of transition-metal complexes and their unique properties. IMPACT OF DISCOVERIES Discoveries of ferrocene and Ziegler catalys...