نتایج جستجو برای: transient ischemia

تعداد نتایج: 204291  

Journal: :Stroke 2015
Jason K Wasserman Jeffrey J Perry Marco L A Sivilotti Jane Sutherland Andrew Worster Marcel Émond Albert Y Jin Wieslaw J Oczkowski Demetrios J Sahlas Heather Murray Ariane MacKey Steve Verreault George A Wells Dar Dowlatshahi Grant Stotts Ian G Stiell Mukul Sharma

BACKGROUND AND PURPOSE Ischemia on computed tomography (CT) is associated with subsequent stroke after transient ischemic attack. This study assessed CT findings of acute ischemia, chronic ischemia, or microangiopathy for predicting subsequent stroke after transient ischemic attack. METHODS This prospective cohort study enrolled patients with transient ischemic attack or nondisabling stroke t...

Objective(s): Obestatin is a newly discovered peptide with antioxidant activities in different animal models. Recent studies have shown that Obestatin inhibits apoptosis following cardiac ischemia/reperfusion injury. Brain ischemia/reperfusion induces irreversible damage especially in the hippocampus area. This study aimed at examining the protective impact of Obestati...

2017
Jae-Chul Lee Yang Hee Kim Tae-Kyeong Lee In Hye Kim Jeong Hwi Cho Geum-Sil Cho Bich-Na Shin Joon Ha Park Ji Hyeon Ahn Myoung Cheol Shin Jun Hwi Cho Il Jun Kang Moo-Ho Won Jeong Yeol Seo

Ischemic preconditioning (IPC) is induced by exposure to brief durations of transient ischemia, which results in ischemic tolerance to a subsequent longer or lethal period of ischemia. In the present study, the effects of IPC (2 min of transient cerebral ischemia) were examined on immunoreactivity of platelet‑derived growth factor (PDGF)‑BB and on neuroprotection in the gerbil hippocampal CA1 r...

2013
Ji-hoon Kim Dong Gyu Na Kee-Hyun Chang In Chan Song Seung Hong Choi Kyu Ri Son Kyung Won Kim Chul Ho Sohn

OBJECTIVE To evaluate the temporal evolution and diagnostic values of the diffusion tensor imaging (DTI) and the high b value diffusion weighted imaging (DWI) in the early permanent and transient cerebral ischemia. MATERIALS AND METHODS For permanent or 30-minute transient-ischemia induced 30 rats, DTI and DWIs at both high b (b = 3000 s/mm(2)) and standard b value (b = 1000 s/mm(2)) were obt...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2000
A Tsujikawa J Kiryu A Nonaka K Yamashiro H Nishiwaki Y Honda Y Ogura

Diabetes is associated with increased neural damage after transient cerebral ischemia. Recently, leukocytes, which are thought to play a central role in ischemia-reperfusion injury, have been suggested to be involved in exacerbated damage after transient ischemia in diabetic animals. The present study was designed to clarify whether the anticipated worse outcome after transient cerebral ischemi...

Journal: :Stroke 2011
Cecil D Hahn Cedric Manlhiot Michael R Schmidt Torsten T Nielsen Andrew N Redington

BACKGROUND AND PURPOSE Remote ischemic preconditioning is a phenomenon by which a short period of sublethal ischemia to an organ protects against subsequent ischemia in another organ. We have recently demonstrated that remote ischemic conditioning by transient hind limb ischemia delivered during ischemia and before reperfusion can provide potent cardioprotection, a phenomenon we termed per-cond...

2014
Tianfei Luo Guiying Liu Hongxi Ma Bin Lu Haiyang Xu Yujing Wang Jiang Wu Pengfei Ge Jianmin Liang

Lethal autophagy is a pathway leading to neuronal death caused by transient global ischemia. In this study, we examined the effect of Ginsenoside Rb1 (GRb1) on ischemia/reperfusion-induced autophagic neuronal death and investigated the role of PI3K/Akt. Ischemic neuronal death in vitro was induced by using oxygen glucose deprivation (OGD) in SH-SY5Y cells, and transient global ischemia was prod...

2016
Robert P Ostrowski Katarzyna Stępień Emanuela Pucko Ewa Matyja

The effectiveness and efficacy of hyperbaric oxygen (HBO) preconditioning and post-treatment modalities have been demonstrated in experimental models of ischemic cerebrovascular diseases, including global brain ischemia, transient focal and permanent focal cerebral ischemia, and experimental neonatal hypoxia-ischemia encephalopathy. In general, early and repetitive post-treatment of HBO appears...

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