background and objective: patients with thalassemia major have an abnormality in hemoglobin synthesis and ineffective hematopoiesis and for this reason with respect to disease severity should receive one or more fresh blood unit every 15-30 days. since transfusion of blood products has been known as one of the routes of hiv infection, therefore, this study was conducted to evaluate the prevalen...

conclusions: hydroxyurea can be safely used in some transfusion-dependent β-thalassemia patients to decrease their transfusion needs. background: β-thalassemia is an inherited hemoglobin disorder caused by defective synthesis of ß-globin chains. hemoglobin (hb) f induction is a possible therapeutic approach which can partially compensate for α and non-α globin chains imbalance. objectives: we a...

800x600 background : hepatitis b and c infections have remained major global health burdens during the most recent century. the viral agents responsible for these diseases share common modes of transmission with human immunodeficiency virus (hiv) such as needle-sharing in iv drug abusers. coinfection of hepatitis b or c with hiv increases the rate of progression of chronic liver disease. given ...

transfusion of blood and its components/derivatives is a life saving medical intervention. however, this life saving procedure depends mainly on the availability of sufficient blood and its components in national health sector. therefore the overall safety of transfusion medicines including the safety of blood and its available components and the appropriate use of these components would direct...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 blood and blood products should be kept in cold temperatures to avoid hemolysis and preserve sterility and functional integrity of blood components. patients needing massive transfusion require the blood to be warmed at bedside, to avoid cardiac and general hypothermia. hypothermia due to massive and rapid transfusion in i...

abstract background multiple transfusions in thalassemia patients may lead to antibody production against blood group antigens and hemolytic transfusion reaction might occur. in this study, antibody screening test was performed by tube and gel methods to determine the prevalence and specificity of alloantibodies in thalassemia patients. materials and methods in this cross-sectional study, overa...

accidental overdose of chemotherapy drugs including vinblastin (vbl) have been reported in the literature. as vbl overdose is potentially fatal, we decided to introduce a 2-year-old girl affected by langerhans’ cell histiocytosis who was accidentally injected 10-times the prescribed dose of vbl (16 mg), and was saved with whole blood double exchange transfusion at 8 and 20 hrs after the acciden...

background: ovarian hyperstimulation syndrome (ohss) is a recognized complication of ovulation induction, occurring in 1-10% of ivf and embryo transfer cycles. while mild ohss is of no clinical relevance, severe ohss is a life threatening complication. however, the efficacy of prevalent treatments appeared to be limited. we developed a continuous autotransfusion system with an ultrafiltration i...

Background: Red blood cell and other blood products play a crucial role in management of different disease processes, but in spite of implementation of crucial steps to improve the process of request for blood and blood consumption, there is still not enough information available regarding the proper practice in many medical centres. We aimed to evaluate the status of blood product requests and...