Binding of the TATA-binding protein (TBP) to the "TATA" sequences present in the promoters of eukaryotic class II genes is the first step in the sequential assembly of transcription pre-initiation complexes. Myriad structural changes, including severe bending of the DNA, accompany TBP-TATA complex formation. A detailed kinetic study has been conducted to elucidate the mechanistic details of TBP...

the thermo-hydraulic behavior of the air flow over a two dimensional ribbed channel wasnumerically investigated in various rib-width ratio configurations (b/h=0.5-1.75) atdifferent reynolds numbers, ranging from 6000 to 18000. the capability of differentturbulence models, including standard k-ε, rng k-ε, standard k-ω, and sst k-ω, inpredicting the heat transfer rate was compared with the experi...

This computational fluid dynamic analysis attempts to simulate the incompressible steady fluid flow and heat transfer in a solar air channel with wall-mounted baffles. Two ꞌSꞌ-shaped baffles, having different orientations, i.e., ꞌSꞌ-upstream and ꞌSꞌ-downstream, were inserted into the channel and fixed to the top and bottom walls of the channel in a periodically staggered manner to develop vorti...

The present paper reports the laminar fluid flow and heat transfer of a heated array of circular-perforated and solid fins mounted over a flat surface using the finite-volume method. One to four circular cross-sectional perforations are made along the length of the fins. The SIMPLE algorithm is used for pressure-velocity coupling and the second order upwind technique is employed to discreti...

Agricultural intensification is associated with the use of great amounts of agrochemicals that may result in the accumulation of metals in soils, and –subsequently—agricultural products and food chain. Nowadays, this is a major concern for many Iranian agricultural products, necessitating scientific researches on the issue. Therefore, the present study has been conducted to evaluate the level o...

This study numerically investigated heat transfer and fluid flow characteristics in a novel cylindrical heat sink with helical minichannels for the laminar flow of fluid with temperature-dependent properties. A finite volume method was employed to obtain the solution of governing equations. The effects of helical angle, channel aspect ratio, and Reynolds number, which were regarded as main para...